Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 1/20 | 0.42 |
| ▸ | CES1 | P23141 | 1/20 | 0.42 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.41 |
| ▸ | DPP4 | P27487 | 7/20 | 0.39 |
| ▸ | DPP7 | Q9UHL4 | 5/20 | 0.39 |
| ▸ | FAP | Q12884 | 3/20 | 0.39 |
| ▸ | DPP8 | Q6V1X1 | 3/20 | 0.39 |
| ▸ | PREP | P48147 | 2/20 | 0.39 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.39 |
| ▸ | PITRM1 | Q5JRX3 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 3/20 | 0.35 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6651288 | 1.00 | CES2 (0.42) | CES2CES1SLC7A5DPP4DPP7 | |
| SCHEMBL2768837 | 0.98 | SLC7A5 (0.42) | CES2CES1SLC7A5DPP4DPP7 | |
| Hydrochloric Acid SCHEMBL1509633 | 0.96 | SLC7A5 (0.41) | CES2CES1SLC7A5DPP4DPP7 | |
| SCHEMBL13759725 | 0.89 | SLC7A5 (0.46) | SLC7A5DPP4DPP7FAPDPP8 | |
| SCHEMBL29779928 | 0.85 | CES2 (0.41) | CES2CES1DPP4DPP7PREP | |
| SCHEMBL22507708 | 0.82 | CES2 (0.46) | CES2CES1DPP4DPP7FAP | |
| SCHEMBL6312834 | 0.82 | CES2 (0.46) | CES2CES1DPP4DPP7FAP | |
| SCHEMBL21445109 | 0.82 | CES2 (0.46) | CES2CES1DPP4DPP7FAP | |
| SCHEMBL30988890 | 0.82 | CES2 (0.46) | CES2CES1DPP4DPP7FAP | |
| SCHEMBL17599037 | 0.79 | CES2 (0.42) | CES2CES1DPP4DPP7FAP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6716878-B1 | BACTERICIDE, ANTIPROTOZOAL; VANCOMYCIN RESISTANT ENTEROCOCCI AND BETA-LACTAM ANTIBIOTIC-RESISTANT BACTERIA, METHICILLIN-RESISTANT STAPHYLOCOCCUS AUREUS; HYDROXAMIC ACID AND N-FORMYL SUBTITUTED ALKYLAMIDES | VERNALIS (OXFORD) LIMITED (GB) | 2004-04-06 | — | — | US | disclosed |
| EP-1169031-A1 | ANTIMICROBIAL AGENTS | BRITISH BIOTECH PHARMACEUTICALS LIMITED (GB) | 2002-01-09 | — | — | EP | disclosed |
| WO-2000061134-A1 | ANTIMICROBIAL AGENTS | BRITISH BIOTECH PHARMACEUTICALS LIMITED (GB) | 2000-10-19 | — | — | WO | disclosed |