SCHEMBL6760299

SCHEMBL6760299

CC(=O)C(C)(Cl)CC(C)(Cl)C(C)=O

nearest known ligand 0.35

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
CA4 P22748 2/20 0.35
GAA P10253 1/20 0.35
CA1 P00915 1/20 0.32
ALDH1A1 P00352 3/20 0.30
TDP1 Q9NUW8 1/20 0.30
THRB P10828 1/20 0.30
TP53 P04637 1/20 0.30
TSHR P16473 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7066509 0.79
SCHEMBL7067794 0.75
SCHEMBL8558705 0.72
SCHEMBL538844 0.72
SCHEMBL7068145 0.71 CES1 (0.41) ALDH1A1TP53TSHR
SCHEMBL11271578 0.71 NAALAD2 (0.42) GAAALDH1A1TDP1THRBTSHR
Trichloroethane SCHEMBL11686802 0.68
SCHEMBL136756 0.68
Trichloroethane SCHEMBL9544417 0.67 TSHR (0.43) CA4GAAALDH1A1TDP1THRB
SCHEMBL11836932 0.67

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6716918-B2 ATOM TRANSFER RADICAL POLYMERIZATION IN THE PRESENCE OF A REDOX CATALYST OF A TRANSITION METAL COMPLEX ALSO USING AN ORGANOHALOGEN OR HALOGENATED SULFONYL COMPOUND AS A POLYMERIZATION CATALYST MITSUBISHI CHEMICAL CORPORATION (JP) 2004-04-06 US disclosed
US-20020156196-A1 Methacrylate-based polymer and process for producing the same MITSUBISHI CHEMICAL CORPORATION (JP) 2002-10-24 US disclosed