Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES1 | P23141 | 6/20 | 0.41 |
| ▸ | CES2 | O00748 | 7/20 | 0.40 |
| ▸ | FDPS | P14324 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | SMPD1 | P17405 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7067794 | 0.85 | — | — | |
| SCHEMBL607576 | 0.81 | FDPS (0.40) | FDPSALDH1A1TP53TSHR | |
| SCHEMBL607577 | 0.81 | FDPS (0.40) | FDPSALDH1A1TP53TSHR | |
| SCHEMBL108941 | 0.75 | CES1 (0.39) | CES1CES2FDPSALDH1A1 | |
| SCHEMBL6048466 | 0.75 | CES1 (0.39) | CES1CES2FDPSALDH1A1 | |
| SCHEMBL28220444 | 0.74 | FDPS (0.42) | CES2FDPSALDH1A1TSHRSMPD1 | |
| SCHEMBL28835881 | 0.74 | TSHR (0.38) | CES1CES2FDPSALDH1A1TP53 | |
| SCHEMBL7066509 | 0.74 | — | — | |
| SCHEMBL1784812 | 0.73 | CES1 (0.37) | CES1CES2FDPSALDH1A1 | |
| SCHEMBL7065199 | 0.73 | CES1 (0.37) | CES1CES2FDPSALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1017679-B1 | PROCESS FOR THE PREPARATION OF IMIDAZOLINE DERIVATIVES | UNIROYAL CHEM CO INC (US) | 2003-06-04 | — | — | EP | disclosed |
| EP-1017679-A1 | PROCESS FOR THE PREPARATION OF IMIDAZOLINE DERIVATIVES | UNIROYAL CHEMICAL COMPANY, Inc. (US) | 2000-07-12 | — | — | EP | disclosed |
| WO-1999016754-A1 | PROCESS FOR THE PREPARATION OF IMIDAZOLINE DERIVATIVES | UNIROYAL CHEMICAL COMPANY, INC. (US) | 1999-04-08 | — | — | WO | disclosed |
| US-5849929-A | Process for the preparation of imidazoline nitroxyl | UNIROYAL CHEMICAL COMPANY, INC. (US) | 1998-12-15 | — | — | US | disclosed |
| US-4240983-A | HALOGENATION | BAYER AKTIENGESELLSCHAFT (DE) | 1980-12-23 | — | — | US | disclosed |