SCHEMBL6760351

SCHEMBL6760351

Cc1cc(OCc2ccccc2/C=C/C(=O)O)c(N(CC(C)C)S(=O)(=O)c2nccs2)cc1C

nearest known ligand 0.57

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
PTGER4 P35408 9/20 0.38
PTGER3 P43115 9/20 0.38
PTGER2 P43116 9/20 0.38
PTGER1 P34995 7/20 0.38
RECQL P46063 1/20 0.35
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL214606 0.87 RECQL (0.38) RECQL
SCHEMBL214605 0.87 RECQL (0.38) RECQL
SCHEMBL213563 0.85 AKR1C3 (0.38)
SCHEMBL213562 0.85 AKR1C3 (0.38)
SCHEMBL215320 0.81 MCL1 (0.36)
SCHEMBL214578 0.80 MCL1 (0.35)
SCHEMBL213113 0.79 NR1H4 (0.43)
SCHEMBL214486 0.79 RECQL (0.35) RECQLMEN1KMT2A
SCHEMBL214485 0.79 RECQL (0.35) RECQLMEN1KMT2A
SCHEMBL214579 0.79 RORC (0.35) MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20040082653-A1 Remedies for depression containing ep1 antagonist as the active ingredient ONO PHARMACEUTICAL CO., LTD. (JP) 2004-04-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040082653-A1 Remedies for depression containing ep1 antagonist as the active ingredient PTGER1, PTGER2, PTGS1 PTGER4 5/4885PTGER3 6/4885PTGER2 2/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.