Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.45 |
| ▸ | CA2 | P00918 | 2/20 | 0.45 |
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.45 |
| ▸ | PARP1 | P09874 | 1/20 | 0.45 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.45 |
| ▸ | PARP4 | Q9UKK3 | 1/20 | 0.45 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.45 |
| ▸ | CNR1 | P21554 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.42 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.42 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.42 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.42 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6760928 | 1.00 | CA1 (0.45) | CA1CA2PARP10PARP1PARP2 | |
| SCHEMBL6760930 | 1.00 | CA1 (0.45) | CA1CA2PARP10PARP1PARP2 | |
| SCHEMBL7180064 | 0.89 | TBXAS1 (0.56) | CA1CA2TBXAS1CNR1ALDH1A1 | |
| SCHEMBL7180077 | 0.89 | TBXAS1 (0.56) | CA1CA2TBXAS1CNR1ALDH1A1 | |
| SCHEMBL7180072 | 0.89 | TBXAS1 (0.56) | CA1CA2TBXAS1CNR1ALDH1A1 | |
| SCHEMBL6763377 | 0.88 | CNR1 (0.46) | TBXAS1CNR1ALDH1A1LMNAHDAC1 | |
| SCHEMBL6763375 | 0.88 | CNR1 (0.46) | TBXAS1CNR1ALDH1A1LMNAHDAC1 | |
| SCHEMBL6763373 | 0.88 | CNR1 (0.46) | TBXAS1CNR1ALDH1A1LMNAHDAC1 | |
| SCHEMBL6763382 | 0.85 | TBXAS1 (0.42) | TBXAS1CNR1ALDH1A1LMNAHDAC1 | |
| SCHEMBL6763384 | 0.85 | TBXAS1 (0.42) | TBXAS1CNR1ALDH1A1LMNAHDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040034097-A1 | Pesticidal activity of functionalized alkenes | LINDERMAN RUSSELL J (US) | 2004-02-19 | — | — | US | claimed |
| US-6660770-B2 | Inhibit digestion by terminating or blocking synthesis of digestive enzymes by activating trypsin modulating oostatic factor receptor | NORTH CAROLINA STATE UNIVERSITY | 2003-12-09 | — | — | US | claimed |
| EP-1241941-B1 | PESTICIDAL ACTIVITY OF FUNCTIONALIZED ALKENES | UNIV NORTH CAROLINA STATE (US) | 2003-06-18 | — | — | EP | claimed |
| US-6521664-B1 | Pesticidal activity of functionalized alkenes | NORTH CAROLINA STATE UNIVERSITY | 2003-02-18 | — | — | US | claimed |
| US-20020193436-A1 | Pesticidal activity of functionalized alkenes | NORTH CAROLINA STATE UNIVERSITY | 2002-12-19 | — | — | US | claimed |
| WO-2002098220-A2 | PESTICIDAL ACTIVITY OF FUNCTIONALIZED ALKENES | NORTH CAROLINA STATE UNIVERSITY (US) | 2002-12-12 | — | — | WO | claimed |
| EP-1241941-A2 | PESTICIDAL ACTIVITY OF FUNCTIONALIZED ALKENES | NORTH CAROLINA STATE UNIVERSITY (US) | 2002-09-25 | — | — | EP | claimed |
| WO-2001041543-A2 | PESTICIDAL ACTIVITY OF FUNCTIONALIZED ALKENES | NORTH CAROLINA STATE UNIVERSITY (US) | 2001-06-14 | — | — | WO | claimed |
| US-20040034097-A1 | Pesticidal activity of functionalized alkenes | LINDERMAN RUSSELL J (US) | 2004-02-19 | — | — | US | disclosed |
| US-6660770-B2 | Inhibit digestion by terminating or blocking synthesis of digestive enzymes by activating trypsin modulating oostatic factor receptor | NORTH CAROLINA STATE UNIVERSITY | 2003-12-09 | — | — | US | disclosed |
| EP-1241941-B1 | PESTICIDAL ACTIVITY OF FUNCTIONALIZED ALKENES | UNIV NORTH CAROLINA STATE (US) | 2003-06-18 | — | — | EP | disclosed |
| US-6521664-B1 | Pesticidal activity of functionalized alkenes | NORTH CAROLINA STATE UNIVERSITY | 2003-02-18 | — | — | US | disclosed |
| US-20020193436-A1 | Pesticidal activity of functionalized alkenes | NORTH CAROLINA STATE UNIVERSITY | 2002-12-19 | — | — | US | disclosed |
| WO-2002098220-A2 | PESTICIDAL ACTIVITY OF FUNCTIONALIZED ALKENES | NORTH CAROLINA STATE UNIVERSITY (US) | 2002-12-12 | — | — | WO | disclosed |
| EP-1241941-A2 | PESTICIDAL ACTIVITY OF FUNCTIONALIZED ALKENES | NORTH CAROLINA STATE UNIVERSITY (US) | 2002-09-25 | — | — | EP | disclosed |
| WO-2001041543-A2 | PESTICIDAL ACTIVITY OF FUNCTIONALIZED ALKENES | NORTH CAROLINA STATE UNIVERSITY (US) | 2001-06-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020193436-A1 | Pesticidal activity of functionalized alkenes | VIP, ANPEP, APEH | CA1 2615/4885CA2 1474/4885PARP10 4200/4885 |
| US-20040034097-A1 | Pesticidal activity of functionalized alkenes | VIP, ANPEP, APEH | CA1 2615/4885CA2 1474/4885PARP10 4200/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.