Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 1/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.46 |
| ▸ | FAAH | O00519 | 1/20 | 0.46 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | SSTR5 | P35346 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | LTA4H | P09960 | 1/20 | 0.44 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.43 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.43 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6761400 | 1.00 | NR4A2 (0.46) | NR4A2EPHX2FAAHENPP2KMT2A | |
| SCHEMBL6763055 | 0.91 | KMT2A (0.51) | KMT2AMAPTSMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL6763048 | 0.91 | KMT2A (0.51) | KMT2AMAPTSMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL6763172 | 0.87 | POLB (0.46) | EPHX2KMT2AMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL6761926 | 0.87 | KMT2A (0.47) | KMT2AMAPTSMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL6761923 | 0.87 | KMT2A (0.47) | KMT2AMAPTSMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL6760373 | 0.87 | CCR1 (0.47) | EPHX2KMT2AMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL6763166 | 0.87 | POLB (0.46) | EPHX2KMT2AMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL6760372 | 0.87 | CCR1 (0.47) | EPHX2KMT2AMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL6765088 | 0.86 | EPHX2 (0.47) | EPHX2ENPP2KMT2AMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040063688-A1 | Novel piperidine derivatives | PFIZER INC. | 2004-04-01 | — | — | US | claimed |
| US-20040063688-A1 | Novel piperidine derivatives | PFIZER INC. | 2004-04-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040063688-A1 | Novel piperidine derivatives | CCR1, CCR3, CCR2 | NR4A2 515/4885EPHX2 3279/4885FAAH 2014/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.