SCHEMBL6761972

SCHEMBL6761972

CC1=C(C)C([Cr])(Cc2ccc3ccccc3n2)C(C)=C1C

nearest known ligand 0.43

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 2/20 0.43
CYSLTR1 Q9Y271 2/20 0.41
CYSLTR2 Q9NS75 1/20 0.41
PDE10A Q9Y233 5/20 0.41
KDM4E B2RXH2 1/20 0.40
ALDH1A1 P00352 1/20 0.40
BRD4 O60885 1/20 0.37
NCF1 P14598 1/20 0.37
GPBAR1 Q8TDU6 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6758512 0.81 CYP1A2 (0.43) CYP1A2CYSLTR1CYSLTR2PDE10AKDM4E
Hydrochloric Acid SCHEMBL6751614 0.79 CYP1A2 (0.42) CYP1A2CYSLTR1CYSLTR2PDE10AKDM4E
SCHEMBL6761970 0.77 CYP1A2 (0.43) CYP1A2CYSLTR1CYSLTR2PDE10AKDM4E
SCHEMBL6751584 0.73 ALDH1A1 (0.39) CYP1A2CYSLTR1CYSLTR2PDE10AKDM4E
SCHEMBL153778 0.73 CYSLTR1 (0.53) CYP1A2CYSLTR1CYSLTR2PDE10ANCF1
SCHEMBL29405396 0.73 CYSLTR1 (0.53) CYP1A2CYSLTR1CYSLTR2PDE10ANCF1
Hydrochloric Acid SCHEMBL28245253 0.71 CYSLTR1 (0.52) CYP1A2CYSLTR1CYSLTR2PDE10ANCF1
Iodide SCHEMBL28612904 0.71 CYSLTR1 (0.52) CYP1A2CYSLTR1CYSLTR2PDE10ANCF1
Ammonia Solution, Strong SCHEMBL28282609 0.71 CYSLTR1 (0.52) CYP1A2CYSLTR1CYSLTR2PDE10ANCF1
Hydrochloric Acid SCHEMBL5197438 0.71 CYSLTR1 (0.52) CYP1A2CYSLTR1CYSLTR2PDE10ANCF1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6723675-B1 IMPREGNATING OR SPRAY-DRYING CATALYST COMPOUND COMPRISING GROUP 4, 5, 6 TRANSITION METAL COMPLEX ON SUPPORT UNIVATION TECHNOLOGIES, LLC 2004-04-20 US disclosed
WO-2001092346-A2 CATALYST FOR THE PRODUCTION OF OLEFIN POLYMERS UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) 2001-12-06 WO disclosed