Known targets — ChEMBL curated mechanism
MMP1MMP13MMP7MMP8polrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Phenolphthalein. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.85 |
| ▸ | LMNA | P02545 | 4/20 | 0.85 |
| ▸ | MEN1 | O00255 | 3/20 | 0.85 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.85 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.85 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.85 |
| ▸ | GPR55 | Q9Y2T6 | 2/20 | 0.85 |
| ▸ | TYMS | P04818 | 2/20 | 0.85 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.85 |
| ▸ | ESR1 | P03372 | 1/20 | 0.85 |
| ▸ | TP53 | P04637 | 1/20 | 0.85 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.85 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.85 |
| ▸ | TSHR | P16473 | 1/20 | 0.85 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.85 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.85 |
| ▸ | CFTR | P13569 | 1/20 | 0.63 |
| ▸ | GOPC | Q9HD26 | 1/20 | 0.63 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.63 |
| ▸ | POLB | P06746 | 3/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phenolphthalein SCHEMBL9755053 | 0.92 | MAPT (0.93) | MAPTLMNAMEN1KMT2ATDP1 | |
| Phenolphthalein SCHEMBL27670 | 0.92 | MAPT (1.00) | MAPTLMNAMEN1KMT2ATDP1 | |
| Phenolphthalein SCHEMBL29362413 | 0.92 | MAPT (1.00) | MAPTLMNAMEN1KMT2ATDP1 | |
| Phenolphthalein SCHEMBL6139696 | 0.92 | MAPT (1.00) | MAPTLMNAMEN1KMT2ATDP1 | |
| Phenolphthalein SCHEMBL23929043 | 0.91 | MAPT (0.97) | MAPTLMNAMEN1KMT2ATDP1 | |
| Phenolphthalein SCHEMBL5958114 | 0.91 | MAPT (0.97) | MAPTLMNAMEN1KMT2ATDP1 | |
| Phenolphthalein SCHEMBL3420446 | 0.91 | MAPT (0.97) | MAPTLMNAMEN1KMT2ATDP1 | |
| Phenolphthalein SCHEMBL951288 | 0.91 | MAPT (0.97) | MAPTLMNAMEN1KMT2ATDP1 | |
| Phenolphthalein SCHEMBL4749522 | 0.91 | MAPT (0.97) | MAPTLMNAMEN1KMT2ATDP1 | |
| Phenolphthalein SCHEMBL7479687 | 0.91 | MAPT (0.97) | MAPTLMNAMEN1KMT2ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 633 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118010713-A | Method for rapidly detecting content of silicon dioxide, aluminum oxide and fluorine in lithium concentrate | 紫金铜业有限公司 | 2024-05-10 | — | — | CN | claimed |
| CN-117571698-B | Filling type saturation detection method | 中交一公局西南工程有限公司 | 2024-03-22 | — | — | CN | claimed |
| CN-117723532-A | Method for measuring carbonization depth of artificial coarse aggregate-based concrete | 深圳大学 | 2024-03-19 | — | — | CN | claimed |
| CN-117571698-A | Filling type saturation detection method | 中交一公局西南工程有限公司 | 2024-02-20 | — | — | CN | claimed |
| CN-117168347-B | Pre-buried concrete carbonization depth detection device and use method | 合肥工大共达工程检测试验有限公司 | 2024-02-13 | — | — | CN | claimed |
| CN-117517297-A | Method for detecting carbonization depth of concrete material in reinforced concrete member | 佛山市高恒建设工程质量检测有限公司 | 2024-02-06 | — | — | CN | claimed |
| CN-113916177-B | Concrete dam carbonization depth full life cycle nondestructive testing method | 西安理工大学 | 2024-01-09 | — | — | CN | claimed |
| CN-117250337-A | Concrete carbonization depth measuring device and measuring method | 唐山守信市政工程检测有限公司 | 2023-12-19 | — | — | CN | claimed |
| CN-117168347-A | Pre-buried concrete carbonization depth detection device and use method | 合肥工大共达工程检测试验有限公司 | 2023-12-05 | — | — | CN | claimed |
| CN-113933291-B | High-precision measuring method for carbonization depth of concrete dam | 西安理工大学 | 2023-10-24 | — | — | CN | claimed |
| CN-110658188-A | Concrete carbonization depth detector and detection method | 青岛理工大学 | 2020-01-07 | — | — | CN | claimed |
| CN-107121047-B | A kind of fire-damaged concrete internal temperature field measuring method | 天津市交通科学研究院 | 2019-09-13 | — | — | CN | claimed |
| CN-109668878-A | A kind of enameled wire breakage test equipment and its test method | 优易电缆(张家港)有限公司 | 2019-04-23 | — | — | CN | claimed |
| CN-109186417-A | A kind of multifunctional ruler and its measurement method for concrete carbonization depth measurement | 安徽省建筑工程质量监督检测站 | 2019-01-11 | — | — | CN | claimed |
| CN-107121047-A | A kind of fire-damaged concrete internal temperature field assay method | 天津市交通科学研究院 | 2017-09-01 | — | — | CN | claimed |
| CN-105548166-A | OPA (o-phthalaldehyde) disinfector concentration range detection test paper | GUANGZHOU YIDE BIOTECHNOLOGY CO LTD | 2016-05-04 | — | — | CN | claimed |
| CN-204832189-U | Phenolphthalein alcohol reagent atomizer | HUBEI GEZHOUBA TESTING CO LTD | 2015-12-02 | — | — | CN | claimed |
| CN-104109382-A | Aging self diagnosis composite insulator silicone rubber and preparation method thereof | GPGC ELECTRIC POWER RES INST | 2014-10-22 | — | — | CN | claimed |
| CN-103575871-A | Freeze prevention method for CO2 absorption liquid for in-situ winter soil respiration sample plot monitoring | INST APPLIED ECOLOGY CAS | 2014-02-12 | — | — | CN | claimed |
| CN-1403812-A | Experimental method for determining acid value in oil-bromothymol blue method | CHINA NAT PETROLEUM CORP (CN) | 2003-03-19 | — | — | CN | claimed |