⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL293424 | 0.85 | TAS1R3 (0.33) | — | |
| SCHEMBL270980 | 0.81 | — | — | |
| SCHEMBL3671616 | 0.81 | — | — | |
| SCHEMBL2700418 | 0.80 | — | — | |
| SCHEMBL271367 | 0.77 | PLA2G2C (0.33) | — | |
| SCHEMBL271828 | 0.76 | MAPT (0.36) | — | |
| SCHEMBL277536 | 0.74 | MAPT (0.39) | — | |
| SCHEMBL2702679 | 0.73 | TSHR (0.35) | — | |
| SCHEMBL3965150 | 0.73 | TSHR (0.35) | — | |
| SCHEMBL271666 | 0.71 | PLA2G2C (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040048866-A1 | Indazole derivatives that are activators of soluble guanylate cyclase | ABBOTT LABORATORIES | 2004-03-11 | — | — | US | disclosed |