Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIA4 | P48058 | 2/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.40 |
| ▸ | AKR1C3 | P42330 | 7/20 | 0.37 |
| ▸ | AKR1C2 | P52895 | 7/20 | 0.37 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 4/20 | 0.35 |
| ▸ | CA1 | P00915 | 4/20 | 0.35 |
| ▸ | CA2 | P00918 | 4/20 | 0.35 |
| ▸ | CA4 | P22748 | 4/20 | 0.35 |
| ▸ | CA9 | Q16790 | 4/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.34 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | CDC42 | P60953 | 1/20 | 0.34 |
| ▸ | RAC1 | P63000 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6759452 | 0.82 | GRIA4 (0.41) | GRIA4PTGS2AKR1C3AKR1C2ABCB11 | |
| SCHEMBL6762662 | 0.82 | GRIA4 (0.41) | GRIA4PTGS2AKR1C3AKR1C2ABCB11 | |
| SCHEMBL6575871 | 0.81 | ABCB11 (0.54) | GRIA4PTGS2AKR1C3AKR1C2ABCB11 | |
| SCHEMBL6573583 | 0.79 | GRIA4 (0.48) | GRIA4PTGS2AKR1C3AKR1C2ABCB11 | |
| SCHEMBL6759350 | 0.78 | GRIA4 (0.47) | GRIA4PTGS2AKR1C3AKR1C2ABCB11 | |
| SCHEMBL6572002 | 0.78 | GRIA4 (0.51) | GRIA4PTGS2ABCB11TSHRKDM4E | |
| SCHEMBL6763719 | 0.77 | ACACB (0.47) | GRIA4CA12CA1CA2CA4 | |
| SCHEMBL6762651 | 0.76 | GRIA4 (0.47) | GRIA4PTGS2AKR1C3AKR1C2ABCB11 | |
| SCHEMBL6763754 | 0.75 | CA4 (0.44) | GRIA4PTGS2AKR1C3AKR1C2CA12 | |
| SCHEMBL6762961 | 0.75 | KDM4E (0.44) | GRIA4PTGS2AKR1C3AKR1C2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040147612-A1 | Sulfonamide derivatives | DAVISON JOSHUA ZWICK (US) | 2004-07-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040147612-A1 | Sulfonamide derivatives | GRIN1, GRIN2A, GRIA1 | GRIA4 9/4885PTGS2 959/4885AKR1C3 2419/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.