Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 9/20 | 0.43 |
| ▸ | PTGDR | Q13258 | 4/20 | 0.43 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | CCR1 | P32246 | 3/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | PPARD | Q03181 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | HTR2B | P41595 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6763023 | 1.00 | PTGDR2 (0.43) | PTGDR2PTGDRPTGER2TSHRTDP1 | |
| SCHEMBL6758130 | 0.89 | PTGDR2 (0.45) | PTGDR2PTGDRTSHRCCR1EPHX2 | |
| SCHEMBL6758126 | 0.89 | PTGDR2 (0.45) | PTGDR2PTGDRTSHRCCR1EPHX2 | |
| SCHEMBL6155923 | 0.89 | CCR1 (0.54) | PTGDR2PTGDRTSHRCCR1EPHX2 | |
| SCHEMBL6758127 | 0.89 | CCR1 (0.54) | PTGDR2PTGDRTSHRCCR1EPHX2 | |
| SCHEMBL6155917 | 0.89 | CCR1 (0.54) | PTGDR2PTGDRTSHRCCR1EPHX2 | |
| SCHEMBL6762010 | 0.89 | CCR1 (0.52) | PTGDR2TSHRCCR1EPHX2HTR2C | |
| SCHEMBL6762007 | 0.89 | CCR1 (0.52) | PTGDR2TSHRCCR1EPHX2HTR2C | |
| SCHEMBL6758359 | 0.88 | TSHR (0.43) | PTGDR2TSHRCCR1EPHX2MAPT | |
| SCHEMBL6758352 | 0.88 | TSHR (0.43) | PTGDR2TSHRCCR1EPHX2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040063688-A1 | Novel piperidine derivatives | PFIZER INC. | 2004-04-01 | — | — | US | claimed |
| US-20040063688-A1 | Novel piperidine derivatives | PFIZER INC. | 2004-04-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040063688-A1 | Novel piperidine derivatives | CCR1, CCR3, CCR2 | PTGDR2 628/4885PTGDR 400/4885PTGER2 819/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.