Phenol

Phenol

SCHEMBL6763201

N=S(=O)=O.Oc1ccccc1

nearest known ligand 0.65

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 4/20 0.65
CA2 P00918 4/20 0.65
CA9 Q16790 4/20 0.65
CA14 Q9ULX7 4/20 0.65
CA1 P00915 3/20 0.65
CA3 P07451 3/20 0.65
CA4 P22748 3/20 0.65
TDP1 Q9NUW8 2/20 0.65
GLA P06280 1/20 0.65
MMP3 P08254 1/20 0.46
BCL2L1 Q07817 1/20 0.46
CES2 O00748 1/20 0.44
ESR1 P03372 5/20 0.41
ESR2 Q92731 4/20 0.40
MEN1 O00255 3/20 0.40
KMT2A Q03164 3/20 0.40
NPC1 O15118 2/20 0.40
LTA4H P09960 1/20 0.40
NR1H2 P55055 1/20 0.40
BAX Q07812 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phenol SCHEMBL28182014 0.97 CA12 (0.61) CA12CA2CA9CA14CA1
Phenol SCHEMBL902074 0.85 CA12 (0.69) CA12CA2CA9CA14CA1
Phenol SCHEMBL28101424 0.82 CA12 (0.65) CA12CA2CA9CA14CA1
Phenol SCHEMBL27810625 0.81
Phenol SCHEMBL28282960 0.81
Phenol SCHEMBL5849614 0.81
Phenol SCHEMBL11721197 0.81
Phenol SCHEMBL32679316 0.81 CA12 (0.85) CA12CA2CA9CA14CA1
Phenol SCHEMBL7750141 0.80 CA12 (1.00) CA12CA2CA9CA14CA1
Phenol SCHEMBL28575 0.80 CA12 (1.00) CA12CA2CA9CA14CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6727359-B2 REACTING PHENOXIDE SULFONYLCHLORIDE AND ACETOACETAMIDE-N-SULFONYL PHENOXIDE AND AMMONIA USING CATALYST BDL CORPORATION 2004-04-27 US claimed
US-20030065172-A1 Composition comprising 6-methyl-3,4dihydro-1,2,3-oxathiazin-4-one-2,2-dioxide, its salts, preparation thereof and uses therefor BDL CORPORATION 2003-04-03 US claimed
US-6727359-B2 REACTING PHENOXIDE SULFONYLCHLORIDE AND ACETOACETAMIDE-N-SULFONYL PHENOXIDE AND AMMONIA USING CATALYST BDL CORPORATION 2004-04-27 US disclosed
US-20030065172-A1 Composition comprising 6-methyl-3,4dihydro-1,2,3-oxathiazin-4-one-2,2-dioxide, its salts, preparation thereof and uses therefor BDL CORPORATION 2003-04-03 US disclosed
EP-0294785-B1 MAGENTA DYE-FORMING COUPLER FUJI PHOTO FILM CO., LTD. (JP) 1992-11-25 EP disclosed
US-5116990-A MAGENTA DYE-FORMING COUPLER FUJI PHOTO FILM CO., LTD. (JP) 1992-05-26 US disclosed
US-4874689-A POLYMER COUPLER; CHAIN TRANSFER AGENT FUJI PHOTO FILM CO., LTD. (JP) 1989-10-17 US disclosed
EP-0294785-A2 Magenta dye-forming coupler FUJI PHOTO FILM CO., LTD. (JP) 1988-12-14 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030065172-A1 Composition comprising 6-methyl-3,4dihydro-1,2,3-oxathiazin-4-one-2,2-dioxide, its salts, preparation thereof and uses therefor PDXK, ITK, KHK CA12 2371/4885CA2 1215/4885CA9 2543/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.