SCHEMBL6763909

SCHEMBL6763909

O=CC(=O)c1ccc(C=Cc2ccc(Cl)cc2)cc1

nearest known ligand 0.61

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
MAOB P27338 9/20 0.61
CXCL12 P48061 2/20 0.61
MAOA P21397 3/20 0.59
CYP1B1 Q16678 1/20 0.58
CYP1A2 P05177 1/20 0.53
ALDH1A1 P00352 1/20 0.48
MAPK1 P28482 1/20 0.48
TDP1 Q9NUW8 1/20 0.48
AHR P35869 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1673734 0.89 MAPK1 (0.58) MAOBCXCL12MAOACYP1B1CYP1A2
Water SCHEMBL10353718 0.87 MAPK1 (0.56) MAOBCXCL12MAOACYP1B1CYP1A2
SCHEMBL2864636 0.83 MAPK1 (0.52) MAOBCXCL12MAOACYP1B1CYP1A2
4',4-Dichlorochalcone SCHEMBL659211 0.82 MAOB (0.86) MAOBCXCL12MAOACYP1B1CYP1A2
4',4-Dichlorochalcone SCHEMBL659210 0.82 MAOB (0.86) MAOBCXCL12MAOACYP1B1CYP1A2
SCHEMBL10880349 0.80 MAOB (0.45) MAOBCXCL12MAOACYP1B1ALDH1A1
4',4-Dichlorochalcone SCHEMBL11819608 0.80 MAOB (0.83) MAOBCXCL12MAOACYP1B1CYP1A2
4',4-Dichlorochalcone SCHEMBL11819257 0.80 MAOB (0.83) MAOBCXCL12MAOACYP1B1CYP1A2
4',4-Dichlorochalcone SCHEMBL11819262 0.80 MAOB (0.83) MAOBCXCL12MAOACYP1B1CYP1A2
4',4-Dichlorochalcone SCHEMBL11819602 0.80 MAOB (0.83) MAOBCXCL12MAOACYP1B1CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114384756-A Resin composition, toner for developing electrostatic image, image forming method, photosensitive adhesive, and photoswitch material 柯尼卡美能达株式会社 2022-04-22 CN disclosed
WO-2021075456-A1 PHOTOCHROMIC COMPOUND AND CURABLE COMPOSITION INCLUDING PHOTOCHROMIC COMPOUND 株式会社トクヤマ 2021-04-22 WO disclosed
US-6821643-B1 SATISFACTORY EMISSION IN THE VISIBLE SPECTRUM FROM BLUE TO LONGER WAVELENGTH REGIONS XEROX CORPORATION 2004-11-23 US disclosed
US-6229012-B1 ORGANIC ELECTROLUMINESCENT DEVICES XEROX CORPORATION 2001-05-08 US disclosed
US-6225467-B1 UNIFORM LUMINESCENCE, ELECTROLUMINESCENT EFFICIENCY, DURABILITY, LOW DRIVING VOLTAGE; FOR USE IN FLAT-PANEL EMISSIVE DISPLAY TECHNOLOGIES, INCLUDING TELEVISION SCREENS, COMPUTER SCREENS XEROX CORPORATION 2001-05-01 US disclosed
US-6057048-A Electroluminescent (EL) devices XEROX CORPORATION (US) 2000-05-02 US disclosed