Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 4/20 | 0.43 |
| ▸ | CA1 | P00915 | 4/20 | 0.43 |
| ▸ | CA9 | Q16790 | 4/20 | 0.43 |
| ▸ | PREP | P48147 | 4/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.32 |
| ▸ | IDO1 | P14902 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7855634 | 0.82 | CA12 (0.43) | CA12CA1CA9PREPDRD2 | |
| SCHEMBL6768684 | 0.81 | CA12 (0.44) | CA12CA1CA9PREPDRD2 | |
| SCHEMBL9944001 | 0.80 | HTT (0.34) | CA12CA1CA9PREPDRD2 | |
| SCHEMBL6881796 | 0.79 | CA12 (0.42) | CA12CA1CA9PREPDRD2 | |
| SCHEMBL1070012 | 0.78 | CA12 (0.48) | CA12CA1CA9PREPDRD2 | |
| SCHEMBL6179207 | 0.78 | PREP (0.47) | CA12CA1CA9PREPDRD2 | |
| SCHEMBL24236996 | 0.77 | CA12 (0.42) | CA12CA1CA9PREPDRD2 | |
| SCHEMBL2761534 | 0.76 | CA12 (0.42) | CA12CA1CA9PREPHSP90AA1 | |
| SCHEMBL7778159 | 0.74 | CA12 (0.40) | CA12CA1CA9PREPHSP90AA1 | |
| SCHEMBL19810818 | 0.74 | ALDH1A1 (0.49) | CA12CA1CA9PREPHSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6726911-B1 | SOLVENT EXTRACT; MICROBIOCIDES; ENDOPEPTIDASE, ANGIOTENSIN CONVERTING ENZYME AND SERUM-MEDIATED-BINDING OF LIPOPOLYSACCHARIDE INHIBITORS | GANOMYCIN (DE) | 2004-04-27 | — | — | US | disclosed |
| EP-1158995-B1 | BIOLOGICALLY ACTIVE COMPOUNDS OF GANODERMA PFEIFFERI DMS 13239 | GANOMYCIN GES FUER BIOMEDIZINI (DE) | 2003-06-18 | — | — | EP | disclosed |
| EP-1158995-A1 | BIOLOGICALLY ACTIVE COMPOUNDS OF GANODERMA PFEIFFERI DMS 13239 | Ganomycin Gesellschaft für Biomedizinische Forschung mbH (DE) | 2001-12-05 | — | — | EP | disclosed |
| WO-2000053207-A1 | BIOLOGICALLY ACTIVE COMPOUNDS OF $I(GANODERMA PFEIFFERI) DMS 13239 | GANOMYCIN GESELLSCHAFT FÜR BIOMEDIZINISCHE FORSCHUNG MBH ; (DE) | 2000-09-14 | — | — | WO | disclosed |