Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 3/20 | 0.41 |
| ▸ | GFER | P55789 | 3/20 | 0.41 |
| ▸ | RAD52 | P43351 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.40 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.40 |
| ▸ | HRH4 | Q9H3N8 | 10/20 | 0.39 |
| ▸ | AKT1 | P31749 | 2/20 | 0.38 |
| ▸ | USP28 | Q96RU2 | 1/20 | 0.38 |
| ▸ | USP25 | Q9UHP3 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5964466 | 0.84 | MAPT (0.44) | MAPTKDM4EGAAGFERRAD52 | |
| SCHEMBL5924898 | 0.78 | HRH4 (0.47) | MAPTKDM4EGAAGFERRAD52 | |
| SCHEMBL2636071 | 0.78 | HRH4 (0.54) | MAPTKDM4EGAAGFERALDH1A1 | |
| SCHEMBL22184436 | 0.78 | HRH4 (0.54) | MAPTKDM4EGAAGFERALDH1A1 | |
| SCHEMBL2636329 | 0.77 | GFER (0.47) | MAPTKDM4EGAAGFERRAD52 | |
| SCHEMBL6760036 | 0.77 | CASR (0.41) | MAPTKDM4EGAAGFERRAD52 | |
| Hydrochloric Acid SCHEMBL6376425 | 0.76 | HRH4 (0.52) | MAPTKDM4EGAAGFERALDH1A1 | |
| SCHEMBL6762600 | 0.76 | MAPT (0.42) | MAPTKDM4EGAAGFERRAD52 | |
| SCHEMBL5964548 | 0.74 | GFER (0.39) | MAPTKDM4EGAAGFERRAD52 | |
| SCHEMBL2894910 | 0.74 | MAPT (0.43) | MAPTKDM4EGAAGFERRAD52 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040060127-A1 | Composition for dyeing keratin fibers, comprising at least one para-phenylenediamine derivative comprising a pyrrolidyl group substituted with a silyl radical | L'OREAL S.A. (FR) | 2004-04-01 | — | — | US | claimed |
| US-20040060127-A1 | Composition for dyeing keratin fibers, comprising at least one para-phenylenediamine derivative comprising a pyrrolidyl group substituted with a silyl radical | L'OREAL S.A. (FR) | 2004-04-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040060127-A1 | Composition for dyeing keratin fibers, comprising at least one para-phenylenediamine derivative comprising a pyrrolidyl group substituted with a silyl radical | KRT18, VIM, CDC73 | MAPT 1037/4885KDM4E 1311/4885GAA 4603/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.