Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASR | P41180 | 8/20 | 0.41 |
| ▸ | HRH4 | Q9H3N8 | 6/20 | 0.40 |
| ▸ | GFER | P55789 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.40 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.40 |
| ▸ | CASP6 | P55212 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2636071 | 0.78 | HRH4 (0.54) | HRH4GFERKDM4EGAAMAPT | |
| SCHEMBL22184436 | 0.78 | HRH4 (0.54) | HRH4GFERKDM4EGAAMAPT | |
| SCHEMBL6764157 | 0.77 | MAPT (0.41) | HRH4GFERKDM4EGAAMAPT | |
| Hydrochloric Acid SCHEMBL6376425 | 0.76 | HRH4 (0.52) | HRH4GFERKDM4EGAAMAPT | |
| SCHEMBL6764151 | 0.75 | MAPT (0.41) | HRH4GFERKDM4EGAAMAPT | |
| SCHEMBL5964466 | 0.74 | MAPT (0.44) | HRH4GFERKDM4EGAAMAPT | |
| SCHEMBL5964548 | 0.74 | GFER (0.39) | CASRHRH4GFERKDM4EGAA | |
| SCHEMBL2894910 | 0.74 | MAPT (0.43) | CASRHRH4GFERKDM4EGAA | |
| SCHEMBL6543794 | 0.73 | MAPT (0.46) | HRH4GFERKDM4EGAAMAPT | |
| SCHEMBL5203906 | 0.72 | CASP6 (0.50) | GFERCASP6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040060127-A1 | Composition for dyeing keratin fibers, comprising at least one para-phenylenediamine derivative comprising a pyrrolidyl group substituted with a silyl radical | L'OREAL S.A. (FR) | 2004-04-01 | — | — | US | claimed |
| US-20040060127-A1 | Composition for dyeing keratin fibers, comprising at least one para-phenylenediamine derivative comprising a pyrrolidyl group substituted with a silyl radical | L'OREAL S.A. (FR) | 2004-04-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040060127-A1 | Composition for dyeing keratin fibers, comprising at least one para-phenylenediamine derivative comprising a pyrrolidyl group substituted with a silyl radical | KRT18, VIM, CDC73 | CASR 4817/4885HRH4 1199/4885GFER 2219/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.