Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13012268 | 0.83 | AR (0.77) | ARPGR | |
| SCHEMBL22847930 | 0.80 | MAOB (0.46) | ARPGR | |
| SCHEMBL4195488 | 0.80 | AR (0.52) | ARPGR | |
| SCHEMBL20221049 | 0.79 | AR (0.62) | ARPGR | |
| SCHEMBL13019733 | 0.79 | TRPV4 (0.47) | ARPGR | |
| SCHEMBL4200970 | 0.79 | AR (0.56) | ARPGR | |
| SCHEMBL13945827 | 0.79 | AR (0.61) | ARPGR | |
| SCHEMBL4203274 | 0.79 | AR (0.61) | ARPGR | |
| SCHEMBL13715641 | 0.79 | AR (0.61) | ARPGR | |
| SCHEMBL4206006 | 0.79 | AR (0.61) | ARPGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8183238-B2 | Bicyclic and tricyclic compounds as KAT II inhibitors | PFIZER INC. (US) | 2012-05-22 | — | — | US | disclosed |
| US-20100324043-A1 | Bicyclic And Tricyclic Compounds As KAT II Inhibitors | PFIZER INC | 2010-12-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100324043-A1 | Bicyclic And Tricyclic Compounds As KAT II Inhibitors | KAT2A, KAT2B, KAT6B | AR 2485/4885PGR 2907/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.