Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 16/20 | 0.54 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.50 |
| ▸ | PANK3 | Q9H999 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6764544 | 0.85 | TRPV1 (0.59) | NAMPTTRPV1 | |
| SCHEMBL6764626 | 0.80 | TRPV1 (0.60) | TRPV1PANK3 | |
| SCHEMBL29865257 | 0.78 | CYP11B2 (0.42) | NAMPT | |
| SCHEMBL10285113 | 0.78 | SMN1; SMN2 (0.60) | TRPV1PANK3 | |
| SCHEMBL14040566 | 0.78 | SMN1; SMN2 (0.63) | NAMPTTRPV1PANK3 | |
| SCHEMBL13203001 | 0.77 | PANK3 (0.59) | NAMPTTRPV1PANK3 | |
| SCHEMBL22920552 | 0.73 | PANK3 (0.62) | NAMPTTRPV1PANK3 | |
| SCHEMBL21424078 | 0.72 | PANK3 (0.62) | NAMPTTRPV1PANK3 | |
| SCHEMBL6764523 | 0.71 | NPC1 (0.71) | TRPV1PANK3 | |
| SCHEMBL3699286 | 0.70 | NAMPT (1.00) | NAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8178560-B2 | Therapeutic agents useful for treating pain | PURDUE PHARMA L.P. (US) | 2012-05-15 | — | — | US | disclosed |
| US-8178560-B2 | Therapeutic agents useful for treating pain | PURDUE PHARMA L.P. (US) | 2012-05-15 | — | — | US | disclosed |
| US-20100331369-A1 | Therapeutic Agents Useful for Treating Pain | PURDUE PHARMA L.P. (US) | 2010-12-30 | — | — | US | disclosed |
| US-20100331369-A1 | Therapeutic Agents Useful for Treating Pain | PURDUE PHARMA L.P. (US) | 2010-12-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100331369-A1 | Therapeutic Agents Useful for Treating Pain | GRIN1, GRIK1, GRIN2B | NAMPT 4709/4885TRPV1 135/4885PANK3 4740/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.