SCHEMBL6764709

SCHEMBL6764709

O=Cc1[c]ccc(C=O)c1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 8/20 0.38
KDM4E B2RXH2 1/20 0.38
PTGS2 P35354 1/20 0.38
RAB9A P51151 1/20 0.38
CYP2A6 P11509 6/20 0.35
TSHR P16473 1/20 0.34
HSD17B10 Q99714 2/20 0.33
TDP1 Q9NUW8 2/20 0.33
UNG P13051 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.32
ALDH5A1 P51649 2/20 0.32
ABAT P80404 2/20 0.32
CA12 O43570 1/20 0.32
CA1 P00915 1/20 0.32
CA2 P00918 1/20 0.32
CA9 Q16790 1/20 0.32
AOX1 Q06278 1/20 0.31
TRIM24 O15164 1/20 0.31
HPGD P15428 1/20 0.31
TRIM33 Q9UPN9 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27762365 0.74
SCHEMBL27643662 0.74
SCHEMBL27979986 0.74
SCHEMBL6306865 0.74
SCHEMBL27531279 0.74
SCHEMBL9008015 0.74
SCHEMBL17100968 0.74
SCHEMBL4044708 0.74
SCHEMBL15066587 0.74
SCHEMBL15068112 0.74

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110669058-A Tricyclic quinolone carboxylic acid and preparation method thereof 江西农业大学 2020-01-10 CN claimed
CN-110669058-A Tricyclic quinolone carboxylic acid and preparation method thereof 江西农业大学 2020-01-10 CN disclosed
US-6765089-B1 FOR USE IN THE SYNTHESIS OF PEPTIDES, OLIGOSACCHARIDES, GLYCOPEPTIDES AND GLYCOLIPIDS ALCHEMIA PTY LTD (AU) 2004-07-20 US disclosed
US-6723843-B2 USE OF A 2-SUBSTITUTED-1,3-DIOXOCYCLOALKYL LINKER GROUP TO COUPLE SACCHARIDE GROUPS OF BOTH THE O-GLYCOSIDE AND N-GLYCOSIDE TYPE TO A POLYMER SUPPORT IN A SOLID PHASE SYSTHESIS PROCESS ALCHEMIA PTY LTD (AU) 2004-04-20 US disclosed
US-6573337-B1 Dioxocyclohexane compound linker for solid-phase synthesis of oligosaccharides ALCHEMIA PTY LTD (AU) 2003-06-03 US disclosed
US-20030027925-A1 Oligosaccharide synthesis ALCHEMIA PTY LTD 2003-02-06 US disclosed
EP-0923528-B1 OLIGOSACCHARIDE SYNTHESIS ALCHEMIA PTY LTD (AU) 2002-11-06 EP disclosed
EP-0923528-A4 OLIGOSACCHARIDE SYNTHESIS ALCHEMIA PTY LTD (AU) 2000-07-19 EP disclosed
EP-0923528-A1 OLIGOSACCHARIDE SYNTHESIS Alchemia Pty. Ltd. (AU) 1999-06-23 EP disclosed
WO-1998008799-A1 OLIGOSACCHARIDE SYNTHESIS ALCHEMIA PTY. LTD. (AU) 1998-03-05 WO disclosed