SCHEMBL4044708

SCHEMBL4044708

O=Cc1cc[c]c(F)c1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1418811 0.77
SCHEMBL6764709 0.74 ALDH1A1 (0.38)
SCHEMBL27762365 0.73
SCHEMBL6306865 0.73
SCHEMBL27643662 0.73
SCHEMBL27979986 0.73
SCHEMBL1419668 0.72 KDM4E (0.49)
SCHEMBL1419669 0.72 KDM4E (0.49)
SCHEMBL15067276 0.72 ALDH1A1 (0.41)
SCHEMBL15067275 0.72 ALDH1A1 (0.41)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12011422-B2 Synthetic antibacterial compounds and uses thereof MCMASTER UNIVERSITY (CA) 2024-06-18 US disclosed
US-11866436-B2 Benzo[c][2,6]naphthyridine derivatives, compositions and therapeutic uses thereof CAMBRIDGE ENTERPRISE LIMITED (GB) 2024-01-09 US disclosed
WO-2023186773-A1 SUBSTITUTED 3-AMINO INDAZOLE DERIVATIVES AS KINASE INHIBITORS NERVIANO MEDICAL SCIENCES S.R.L. (IT) 2023-10-05 WO disclosed
US-20230250097-A1 BENZO[C][2,6]NAPHTHYRIDINE DERIVATIVES, COMPOSITIONS AND THERAPEUTIC USES THEREOF Apollo Therapeutics Limited (GB) 2023-08-10 US disclosed
US-20220401384-A1 Synthetic Antibacterial Compounds and Uses Thereof MCMASTER UNIVERSITY (CA) 2022-12-22 US disclosed
CN-107266382-B Heteroarylpiperidine and piperazine derivatives as fungicides 拜耳知识产权有限责任公司 2020-10-27 CN disclosed
US-10426169-B2 Heteroarylpiperidine and -piperazine derivatives as fungicides BAYER INTELLECTUAL PROPERTY GMBH (DE) 2019-10-01 US disclosed
EP-2921485-B1 ISOXAZOLE DERIVATIVES BAYER CROPSCIENCE AG (DE) 2018-07-18 EP disclosed
EP-2921484-B1 OXAZOLE DERIVATIVES BAYER CROPSCIENCE AG (DE) 2018-07-18 EP disclosed
US-20180103641-A1 HETEROARYLPIPERIDINE AND -PIPERAZINE DERIVATIVES AS FUNGICIDES BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2018-04-19 US disclosed
EP-2921492-A1 HETEROARYLPIPERIDINE AND HETEROARYLPIPERAZINE DERIVATIVES Bayer Intellectual Property GmbH (DE) 2015-09-23 EP disclosed
EP-2921493-A1 HETEROARYLPIPERIDINE AND HETEROARYLPIPERAZINE DERIVATIVES Bayer Intellectual Property GmbH (DE) 2015-09-23 EP disclosed
EP-2921494-A1 HETEROARYLPIPERIDINE AND HETEROARYLPIPERAZINE DERIVATIVES Bayer Intellectual Property GmbH (DE) 2015-09-23 EP disclosed
EP-2921495-A1 HETEROARYLPIPERIDINE AND HETEROARYLPIPERAZINE DERIVATIVES AS FUNGICIDES Bayer Intellectual Property GmbH (DE) 2015-09-23 EP disclosed
US-20150024935-A1 HETEROARYLPIPERIDINE AND PIPERAZINE DERIVATIVES AS FUNGICIDES BAYER INTELLECTUAL PROPERTY GMBH (DE) 2015-01-22 US disclosed
EP-2797899-A2 HETEROARYLPIPERIDINE AND PIPERAZINE DERIVATIVES AS FUNGICIDES Bayer Intellectual Property GmbH (DE) 2014-11-05 EP disclosed
WO-2013098229-A2 HETEROARYLPIPERIDINE AND PIPERAZINE DERIVATIVES AS FUNGICIDES BAYER INTELLECTUAL PROPERTY GMBH (DE) 2013-07-04 WO disclosed
US-20090105072-A1 2-(Pyridin-2-Yl)-Pyrimidines for Use as Fungicides BASF SE (DE) 2009-04-23 US disclosed
EP-2010515-A1 2-(PYRIDIN-2-YL)-PYRIMIDINES FOR USE AS FUNGICIDES BASF SE (DE) 2009-01-07 EP disclosed
WO-2007116079-A1 2-(PYRIDIN-2-YL)-PYRIMIDINES FOR USE AS FUNGICIDES BASF SE (DE) 2007-10-18 WO disclosed