Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.70 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.65 |
| ▸ | GAA | P10253 | 2/20 | 0.65 |
| ▸ | LMNA | P02545 | 5/20 | 0.64 |
| ▸ | HPGD | P15428 | 4/20 | 0.64 |
| ▸ | TSHR | P16473 | 1/20 | 0.64 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.64 |
| ▸ | OGG1 | O15527 | 1/20 | 0.62 |
| ▸ | PKM | P14618 | 1/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.60 |
| ▸ | HTT | P42858 | 2/20 | 0.60 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | GLA | P06280 | 1/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4164467 | 0.83 | SMN1; SMN2 (0.62) | SMN1; SMN2ALDH1A1KDM4EGAALMNA | |
| SCHEMBL21056089 | 0.83 | SMN1; SMN2 (0.62) | SMN1; SMN2ALDH1A1KDM4EGAALMNA | |
| SCHEMBL10175710 | 0.82 | ALDH1A1 (0.87) | SMN1; SMN2ALDH1A1KDM4EGAALMNA | |
| SCHEMBL10445559 | 0.81 | SMN1; SMN2 (0.65) | SMN1; SMN2ALDH1A1KDM4EGAALMNA | |
| Rac-Dichlorprop SCHEMBL28260779 | 0.81 | TSHR (0.69) | SMN1; SMN2ALDH1A1KDM4EGAALMNA | |
| SCHEMBL29996006 | 0.81 | SMN1; SMN2 (0.65) | SMN1; SMN2ALDH1A1KDM4EGAALMNA | |
| SCHEMBL29106733 | 0.81 | SMN1; SMN2 (0.65) | SMN1; SMN2ALDH1A1KDM4EGAALMNA | |
| Rac-Dichlorprop SCHEMBL54510 | 0.81 | TSHR (0.73) | SMN1; SMN2ALDH1A1KDM4EGAALMNA | |
| (S)-Dichlorprop SCHEMBL1535831 | 0.81 | TSHR (0.73) | SMN1; SMN2ALDH1A1KDM4EGAALMNA | |
| SCHEMBL6704326 | 0.81 | SMN1; SMN2 (0.64) | SMN1; SMN2ALDH1A1KDM4EGAALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6730704-B2 | REACTING AN ARYLOXYPROPIONIC ACID HYDRAZIDE WITH AN ARYLSULFONYL CHLORIDE | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2004-05-04 | — | — | US | disclosed |
| US-20030187065-A1 | 1-(ARYLOXY)PROPIONOYL-2-ARYLSULFONYL HYDRAZINES, PROCESS FOR PREPARATION THEREOF AND USE THEREOF AS HYPOGLYCEMIC AGENTS | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH | 2003-10-02 | — | — | US | disclosed |
| US-3972905-A | FUNGICIDE | BAYER AKTIENGESELLSCHAFT (DT) | 1976-08-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030187065-A1 | 1-(ARYLOXY)PROPIONOYL-2-ARYLSULFONYL HYDRAZINES, PROCESS FOR PREPARATION THEREOF AND USE THEREOF AS HYPOGLYCEMIC AGENTS | IAPP, DPP4, GLP1R | SMN1; SMN2 4320/4885ALDH1A1 292/4885KDM4E 786/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.