Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | EGFR | P00533 | 3/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.34 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.33 |
| ▸ | ADCY10 | Q96PN6 | 1/20 | 0.33 |
| ▸ | RAF1 | P04049 | 1/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.33 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.33 |
| ▸ | GSK3B | P49841 | 1/20 | 0.33 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.33 |
| ▸ | IDO1 | P14902 | 5/20 | 0.32 |
| ▸ | JAK2 | O60674 | 1/20 | 0.31 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.31 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.31 |
| ▸ | AKT1 | P31749 | 1/20 | 0.30 |
| ▸ | MIF | P14174 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL33794 | 0.78 | EGFR (0.41) | ALDH1A1EGFRMAPK1ADORA1ADCY10 | |
| Hydrochloric Acid SCHEMBL8800846 | 0.76 | EGFR (0.41) | ALDH1A1EGFRMAPK1ADORA1ADCY10 | |
| SCHEMBL9197400 | 0.70 | AKT1 (0.49) | ALDH1A1L3MBTL1EGFRMAPK1ADORA1 | |
| SCHEMBL9282684 | 0.67 | MIF (0.45) | ALDH1A1EGFRADORA1ADORA2AMAPK14 | |
| SCHEMBL20341884 | 0.67 | EGFR (0.38) | ALDH1A1EGFRMAPK1ADORA1ADCY10 | |
| SCHEMBL4408717 | 0.66 | EGFR (0.40) | ALDH1A1EGFRMAPK1ADORA1ADCY10 | |
| SCHEMBL1231181 | 0.66 | EGFR (0.40) | ALDH1A1EGFRMAPK1JAK2MIF | |
| SCHEMBL5847660 | 0.65 | EGFR (0.41) | ALDH1A1L3MBTL1EGFRMAPK1ADORA1 | |
| SCHEMBL16425978 | 0.65 | MIF (0.39) | ALDH1A1EGFRADORA1ADORA2AMIF | |
| SCHEMBL676668 | 0.65 | ALDH1A1 (0.57) | ALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6730789-B1 | RADIATION RESISTANCE, WEATHERPROOF, WASHFASTNESS, COLORFASTNESS; HAIR DYES | L'OREAL S.A. (FR) | 2004-05-04 | — | — | US | claimed |
| US-6730789-B1 | RADIATION RESISTANCE, WEATHERPROOF, WASHFASTNESS, COLORFASTNESS; HAIR DYES | L'OREAL S.A. (FR) | 2004-05-04 | — | — | US | disclosed |