Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 7/20 | 0.39 |
| ▸ | S1PR3 | Q99500 | 6/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | S1PR4 | O95977 | 4/20 | 0.34 |
| ▸ | S1PR5 | Q9H228 | 3/20 | 0.34 |
| ▸ | FAAH | O00519 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | PPARA | Q07869 | 1/20 | 0.34 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6304690 | 0.74 | ALDH1A1 (0.36) | S1PR1S1PR3ALDH1A1MEN1KMT2A | |
| SCHEMBL385680 | 0.73 | S1PR1 (0.41) | S1PR1S1PR3ALDH1A1MEN1KMT2A | |
| SCHEMBL6304687 | 0.72 | ALDH1A1 (0.39) | S1PR1S1PR3ALDH1A1MEN1KMT2A | |
| SCHEMBL384004 | 0.70 | S1PR1 (0.62) | S1PR1S1PR3S1PR4S1PR5 | |
| SCHEMBL383669 | 0.68 | S1PR1 (0.61) | S1PR1S1PR3ALDH1A1S1PR4S1PR5 | |
| SCHEMBL9808262 | 0.65 | MAPT (0.62) | ALDH1A1LMNASMN1; SMN2KCNH2MAPT | |
| SCHEMBL14984020 | 0.63 | MAPT (0.60) | ALDH1A1SMN1; SMN2KCNH2MAPTTDP1 | |
| SCHEMBL30514009 | 0.63 | MAPT (0.60) | ALDH1A1SMN1; SMN2KCNH2MAPTTDP1 | |
| SCHEMBL6269511 | 0.63 | S1PR1 (0.54) | S1PR1S1PR3S1PR4S1PR5TDP1 | |
| SCHEMBL6305559 | 0.62 | KCNA3 (0.42) | S1PR1S1PR3ALDH1A1S1PR4S1PR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6723745-B2 | PREVENTION OR TREATMENT OF AUTOIMMUNE DISEASE IN WARM BLOODED ANIMAL | SANKYO COMPANY, LIMITED (JP) | 2004-04-20 | — | — | US | disclosed |