Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.31 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.31 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.31 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.31 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.31 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.30 |
| ▸ | PSMB11 | A5LHX3 | 1/20 | 0.30 |
| ▸ | PSMD11 | O00231 | 1/20 | 0.30 |
| ▸ | PSMD12 | O00232 | 1/20 | 0.30 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.30 |
| ▸ | PSMA7 | O14818 | 1/20 | 0.30 |
| ▸ | PSMD3 | O43242 | 1/20 | 0.30 |
| ▸ | PSMC3 | P17980 | 1/20 | 0.30 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.30 |
| ▸ | PSMA1 | P25786 | 1/20 | 0.30 |
| ▸ | PSMA2 | P25787 | 1/20 | 0.30 |
| ▸ | PSMA3 | P25788 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6765101 | 0.96 | DPP4 (0.42) | DPP4SMN1; SMN2ALDH1A1CHRNB2CHRNB4 | |
| Oxalic Acid SCHEMBL6765105 | 0.87 | DPP4 (0.40) | DPP4SMN1; SMN2ALDH1A1CHRNB2CHRNB4 | |
| Oxalic Acid SCHEMBL5170460 | 0.82 | DPP4 (0.39) | DPP4SMN1; SMN2ALDH1A1FFAR1HTT | |
| SCHEMBL5165250 | 0.79 | DPP4 (0.37) | DPP4 | |
| SCHEMBL5170465 | 0.78 | DPP4 (0.37) | DPP4SMN1; SMN2ALDH1A1HTT | |
| SCHEMBL6775342 | 0.71 | HCAR2 (0.40) | MMP9 | |
| SCHEMBL6775335 | 0.71 | HCAR2 (0.45) | ALDH1A1MMP9 | |
| SCHEMBL383883 | 0.70 | S1PR4 (0.40) | DPP4SMN1; SMN2ALDH1A1 | |
| SCHEMBL385896 | 0.69 | S1PR1 (0.41) | — | |
| Oxalic Acid SCHEMBL5168183 | 0.69 | PTGER4 (0.38) | DPP4FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6723745-B2 | PREVENTION OR TREATMENT OF AUTOIMMUNE DISEASE IN WARM BLOODED ANIMAL | SANKYO COMPANY, LIMITED (JP) | 2004-04-20 | — | — | US | disclosed |