Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 6/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | NAAA | Q02083 | 1/20 | 0.34 |
| ▸ | MMP3 | P08254 | 1/20 | 0.34 |
| ▸ | MMP9 | P14780 | 1/20 | 0.34 |
| ▸ | MMP8 | P22894 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | AKR1B10 | O60218 | 2/20 | 0.34 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | APEX1 | P27695 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6775342 | 0.97 | HCAR2 (0.40) | HCAR2TDP1L3MBTL1NAAAMMP3 | |
| Fumaric Acid SCHEMBL6775343 | 0.88 | L3MBTL1 (0.39) | HCAR2ALDH1A1TDP1L3MBTL1NAAA | |
| Fumaric Acid SCHEMBL5167568 | 0.82 | L3MBTL1 (0.37) | HCAR2ALDH1A1TDP1L3MBTL1MMP3 | |
| Maleic Acid SCHEMBL5167559 | 0.82 | L3MBTL1 (0.37) | HCAR2ALDH1A1TDP1L3MBTL1MMP3 | |
| SCHEMBL5167563 | 0.82 | HCAR2 (0.36) | HCAR2TDP1L3MBTL1NAAALMNA | |
| SCHEMBL387695 | 0.80 | HCAR2 (0.43) | HCAR2ALDH1A1TDP1LMNA | |
| SCHEMBL6765101 | 0.72 | DPP4 (0.42) | ALDH1A1NAAAMMP9 | |
| SCHEMBL6765094 | 0.71 | DPP4 (0.41) | ALDH1A1MMP9 | |
| SCHEMBL28500283 | 0.67 | HCAR2 (0.77) | HCAR2NAAALMNAAKR1B10AKR1B1 | |
| Hydrochloric Acid SCHEMBL27349461 | 0.67 | HCAR2 (0.77) | HCAR2LMNAAKR1B10AKR1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6723745-B2 | PREVENTION OR TREATMENT OF AUTOIMMUNE DISEASE IN WARM BLOODED ANIMAL | SANKYO COMPANY, LIMITED (JP) | 2004-04-20 | — | — | US | disclosed |