Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | DGKA | P23743 | 2/20 | 0.46 |
| ▸ | LPAR6 | P43657 | 1/20 | 0.44 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.44 |
| ▸ | LPAR4 | Q99677 | 1/20 | 0.44 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.44 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.44 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.44 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.44 |
| ▸ | PRKCA | P17252 | 3/20 | 0.43 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.43 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.43 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5165590 | 0.84 | MAPT (0.52) | MAPTLMNAKDM4EDUSP3MEN1 | |
| SCHEMBL9153115 | 0.77 | MAPT (0.71) | MAPTLMNAKDM4EDUSP3MEN1 | |
| SCHEMBL9149108 | 0.76 | MAPT (0.74) | MAPTLMNAKDM4EDUSP3MEN1 | |
| SCHEMBL9152072 | 0.76 | MAPT (0.74) | MAPTLMNAKDM4EDUSP3MEN1 | |
| SCHEMBL9149118 | 0.76 | MAPT (0.74) | MAPTLMNAKDM4EDUSP3MEN1 | |
| SCHEMBL9151927 | 0.76 | MAPT (0.74) | MAPTLMNAKDM4EDUSP3MEN1 | |
| SCHEMBL9150524 | 0.76 | MAPT (0.74) | MAPTLMNAKDM4EDUSP3MEN1 | |
| SCHEMBL1866206 | 0.76 | MAPT (0.64) | MAPTLMNAKDM4EDUSP3MEN1 | |
| SCHEMBL6578955 | 0.75 | DGKA (0.54) | MAPTLMNAALDH1A1DGKACYP3A4 | |
| SCHEMBL11465997 | 0.74 | MAPT (0.61) | MAPTLMNAKDM4EDUSP3MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6723745-B2 | PREVENTION OR TREATMENT OF AUTOIMMUNE DISEASE IN WARM BLOODED ANIMAL | SANKYO COMPANY, LIMITED (JP) | 2004-04-20 | — | — | US | disclosed |