Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 4/20 | 0.41 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.41 |
| ▸ | ALB | P02768 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | NR2E3 | Q9Y5X4 | 1/20 | 0.40 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.40 |
| ▸ | KCNN3 | Q9UGI6 | 1/20 | 0.39 |
| ▸ | ELANE | P08246 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6481670 | 0.83 | MAOB (0.46) | GAAMAOBALBNPC1RAB9A | |
| SCHEMBL6498257 | 0.83 | PPARG (0.51) | GAAMAOBALBNPC1RAB9A | |
| SCHEMBL6483960 | 0.80 | MAOB (0.45) | GAAMAOBALBPPARGRXFP1 | |
| SCHEMBL6484084 | 0.78 | AHR (0.49) | GAAMAOBNPC1RAB9AMAPT | |
| SCHEMBL6483074 | 0.78 | MAOB (0.49) | GAAMAOBALBMAPTMEN1 | |
| SCHEMBL6486876 | 0.74 | ALDH1A1 (0.41) | GAAMAOBALBNPC1RAB9A | |
| SCHEMBL6484144 | 0.73 | HDAC8 (0.47) | GAAELANEMAPTMEN1KMT2A | |
| SCHEMBL6482983 | 0.73 | MAOB (0.45) | GAAMAOBALBNPC1RAB9A | |
| SCHEMBL6495144 | 0.73 | TP53 (0.48) | GAANPC1RAB9AMAPTMEN1 | |
| SCHEMBL6490881 | 0.73 | MAPT (0.53) | GAAMAOBALBNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6800656-B2 | Tricyclic compounds and method of treating herpes virus | WARNER LAMBERT COMPANY | 2004-10-05 | — | — | US | disclosed |