Known targets — ChEMBL curated mechanism
rplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Stearic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B3 | P37058 | 6/20 | 0.61 |
| ▸ | CES2 | O00748 | 1/20 | 0.55 |
| ▸ | CES1 | P23141 | 1/20 | 0.55 |
| ▸ | PPARA | Q07869 | 7/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.53 |
| ▸ | PPARG | P37231 | 6/20 | 0.53 |
| ▸ | PPARD | Q03181 | 6/20 | 0.53 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.53 |
| ▸ | TSHR | P16473 | 4/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | TLR2 | O60603 | 2/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.53 |
| ▸ | FABP4 | P15090 | 2/20 | 0.53 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.53 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Dodecanoate SCHEMBL6767044 | 1.00 | HSD17B3 (0.61) | HSD17B3CES2CES1PPARAMEN1 | |
| Stearic Acid SCHEMBL9065925 | 0.98 | HSD17B3 (0.59) | HSD17B3CES2CES1PPARAMEN1 | |
| Dodecanoate SCHEMBL29144802 | 0.95 | HSD17B3 (0.67) | HSD17B3PPARAMEN1KMT2AGPR84 | |
| SCHEMBL29908536 | 0.92 | MAPT (0.63) | HSD17B3CES2PPARAMEN1KMT2A | |
| Dodecanoate SCHEMBL6765876 | 0.92 | CES2 (0.64) | CES2CES1PPARAMEN1KMT2A | |
| Sebacic Acid SCHEMBL12971388 | 0.92 | MAPT (0.63) | HSD17B3CES2PPARAMEN1KMT2A | |
| Stearic Acid SCHEMBL6765166 | 0.92 | CES2 (0.64) | CES2CES1PPARAMEN1KMT2A | |
| Sebacic Acid SCHEMBL4288163 | 0.92 | MAPT (0.63) | HSD17B3CES2PPARAMEN1KMT2A | |
| Octanedioate SCHEMBL4274225 | 0.92 | MAPT (0.63) | HSD17B3CES2PPARAMEN1KMT2A | |
| Stearic Acid SCHEMBL28330158 | 0.90 | CES2 (0.62) | CES2CES1PPARAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2992044-B1 | POLYOLEFIN PIPE | UPONOR INNOVATION AB (SE) | 2022-01-12 | — | — | EP | disclosed |
| US-10392496-B2 | Polyolefin pipe | UPONOR INNOVATION AB (SE) | 2019-08-27 | — | — | US | disclosed |
| US-20180258255-A1 | Polyolefin Pipe | UPONOR INNOVATION AB (SE) | 2018-09-13 | — | — | US | disclosed |
| US-9963573-B2 | Polyolefin pipe | UPONOR INNOVATION AB (SE) | 2018-05-08 | — | — | US | disclosed |
| US-20160130420-A1 | Polyolefin Pipe | UPONOR INNOVATION AB (SE) | 2016-05-12 | — | — | US | disclosed |
| EP-2992044-A1 | POLYOLEFIN PIPE | Uponor Innovation AB (SE) | 2016-03-09 | — | — | EP | disclosed |
| WO-2014177435-A1 | POLYOLEFIN PIPE | UPONOR INNOVATION AB (SE) | 2014-11-06 | — | — | WO | disclosed |
| US-20040033380-A1 | Process for the manufacture of thermoplastic shrink films | SYFAN SAAD (99) LTD. (IL) | 2004-02-19 | — | — | US | disclosed |
| EP-1355976-A1 | IMPROVED PROCESS FOR THE MANUFACTURE OF THERMOPLASTIC SHRINK FILMS | Syfan Saad (99) Ltd. (IL) | 2003-10-29 | — | — | EP | disclosed |
| WO-2002051913-A1 | IMPROVED PROCESS FOR THE MANUFACTURE OF THERMOPLASTIC SHRINK FILMS | SYFAN SAAD (99) LTD. (IL) | 2002-07-04 | — | — | WO | disclosed |