Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIA4 | P48058 | 3/20 | 0.43 |
| ▸ | CNR1 | P21554 | 2/20 | 0.38 |
| ▸ | HRAS | P01112 | 1/20 | 0.37 |
| ▸ | KRAS | P01116 | 1/20 | 0.37 |
| ▸ | SLC6A9 | P48067 | 2/20 | 0.37 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 3/20 | 0.37 |
| ▸ | CA4 | P22748 | 3/20 | 0.37 |
| ▸ | CA1 | P00915 | 2/20 | 0.37 |
| ▸ | CA2 | P00918 | 2/20 | 0.37 |
| ▸ | CA9 | Q16790 | 2/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.35 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6759350 | 0.92 | GRIA4 (0.47) | GRIA4HRASKRASSLC6A9CA12 | |
| SCHEMBL6763807 | 0.87 | ALDH1A1 (0.47) | GRIA4HRASKRASSLC6A9CA12 | |
| SCHEMBL6766144 | 0.86 | GRIA4 (0.45) | GRIA4CNR1HRASKRASCYP17A1 | |
| SCHEMBL6765779 | 0.84 | ALDH1A1 (0.52) | GRIA4HRASKRASCA12CA1 | |
| SCHEMBL6763723 | 0.83 | GRIA4 (0.53) | GRIA4CA12CA1CA2CA9 | |
| SCHEMBL6573583 | 0.83 | GRIA4 (0.48) | GRIA4SLC6A9CA12CA4CA1 | |
| SCHEMBL6763719 | 0.82 | ACACB (0.47) | GRIA4CA12CA4CA1CA2 | |
| SCHEMBL6762961 | 0.81 | KDM4E (0.44) | GRIA4PTGS2LMNAHTTAKR1C3 | |
| SCHEMBL6763754 | 0.81 | CA4 (0.44) | GRIA4CA12CA4CA1CA2 | |
| SCHEMBL6761042 | 0.80 | PPARG (0.55) | GRIA4LMNAKDM4EPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040147612-A1 | Sulfonamide derivatives | DAVISON JOSHUA ZWICK (US) | 2004-07-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040147612-A1 | Sulfonamide derivatives | GRIN1, GRIN2A, GRIA1 | GRIA4 9/4885CNR1 62/4885HRAS 3528/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.