Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15916017 | 0.90 | ALOX5AP (1.00) | ALOX5APFEN1 | |
| SCHEMBL15915698 | 0.88 | ALOX5AP (1.00) | ALOX5APFEN1 | |
| SCHEMBL15917570 | 0.88 | ALOX5AP (1.00) | ALOX5APFEN1 | |
| SCHEMBL3831537 | 0.86 | ALOX5AP (0.80) | ALOX5APFEN1 | |
| SCHEMBL15916594 | 0.85 | FEN1 (1.00) | ALOX5APFEN1 | |
| Trifluoroacetic Acid SCHEMBL15917293 | 0.83 | ALOX5AP (0.87) | ALOX5APFEN1 | |
| Trifluoroacetic Acid SCHEMBL15916009 | 0.82 | ALOX5AP (0.86) | ALOX5APFEN1 | |
| SCHEMBL890585 | 0.80 | ALOX5AP (0.65) | ALOX5APFEN1 | |
| SCHEMBL3834597 | 0.80 | ALOX5AP (0.65) | ALOX5APFEN1 | |
| SCHEMBL3833421 | 0.80 | ALOX5AP (0.56) | ALOX5APFEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040116399-A1 | Inhibitors of factor Xa | MILLENNIUM PHARMACEUTICALS, INC. | 2004-06-17 | — | — | US | disclosed |
| US-6720317-B1 | 1-NAPHTH-2-YL-1H-PYRAZOLE-5-(4-AMIDINOPHENYL)CARBOXYAMIDE, MULTIPLY SUBSTITUTED; NON AMIDINO ANTICOAGULANTS; HEMOSTATIC AGENTS | MILLENNIUM PHARMACEUTICALS, INC. | 2004-04-13 | — | — | US | disclosed |
| US-6686368-B1 | Inhibitors of factor Xa | MILLENNIUM PAHRMACEUTICALS, INC. | 2004-02-03 | — | — | US | disclosed |
| US-6632815-B2 | Show selectivity for factor Xa versus other proteases of coagulation or the fibrinolytic cascades | MILLENNIUM PHARMACEUTICALS, INC. | 2003-10-14 | — | — | US | disclosed |
| CN-1390206-A | Inhibitors of factor Xa | COR THERAPEUTICS INC (US) | 2003-01-08 | — | — | CN | disclosed |
| US-20020091116-A1 | Show selectivity for factor Xa versus other proteases of coagulation or the fibrinolytic cascades | MILLENNIUM PHARMACEUTICALS, INC. | 2002-07-11 | — | — | US | disclosed |
| EP-1216231-A2 | INHIBITORS OF FACTOR Xa | Millennium Pharmaceuticals, Inc. (US) | 2002-06-26 | — | — | EP | disclosed |
| WO-2001019798-A2 | INHIBITORS OF FACTOR Xa | COR THERAPEUTICS INC. (US) | 2001-03-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020091116-A1 | Show selectivity for factor Xa versus other proteases of coagulation or the fibrinolytic cascades | SERPINC1, TFPI, F2 | ALOX5AP 948/4885FEN1 507/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.