Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 12/20 | 0.54 |
| ▸ | NR3C1 | P04150 | 6/20 | 0.42 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.42 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.42 |
| ▸ | PGR | P06401 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6766550 | 0.91 | GRM2 (0.62) | GRM2NR3C1LPAR1LPAR5 | |
| SCHEMBL6767469 | 0.89 | GRM2 (0.72) | GRM2 | |
| SCHEMBL6727498 | 0.84 | GRM2 (0.62) | GRM2NR3C1LPAR1LPAR5PGR | |
| SCHEMBL6763463 | 0.84 | GRM2 (0.46) | GRM2LPAR1LPAR5 | |
| SCHEMBL6734022 | 0.83 | GRM2 (0.76) | GRM2NR3C1PGR | |
| SCHEMBL6738944 | 0.82 | GRM2 (0.55) | GRM2NR3C1PGR | |
| SCHEMBL6727601 | 0.80 | GRM2 (0.80) | GRM2NR3C1LPAR1LPAR5PGR | |
| SCHEMBL6767716 | 0.80 | GRM2 (0.79) | GRM2 | |
| SCHEMBL6728181 | 0.79 | GRM2 (0.55) | GRM2NR3C1PGR | |
| SCHEMBL6736012 | 0.78 | GRM2 (0.66) | GRM2NR3C1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6800651-B2 | Potentiators of glutamate receptors | ELI LILLY AND COMPANY | 2004-10-05 | — | — | US | claimed |