Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 6/20 | 0.46 |
| ▸ | BRD4 | O60885 | 1/20 | 0.42 |
| ▸ | LTA4H | P09960 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.38 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.38 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.38 |
| ▸ | MMP2 | P08253 | 1/20 | 0.37 |
| ▸ | MMP9 | P14780 | 1/20 | 0.37 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.37 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | OXTR | P30559 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6768436 | 0.91 | GRM2 (0.54) | GRM2BRD4LTA4HPTGS2LMNA | |
| SCHEMBL6738379 | 0.89 | GRM2 (0.45) | GRM2BRD4NR1H2NR1H3CHRNA7 | |
| SCHEMBL6735511 | 0.85 | HTT (0.56) | GRM2BRD4LMNAGAATSHR | |
| SCHEMBL6766296 | 0.84 | GRM2 (0.54) | GRM2LPAR1LPAR5 | |
| SCHEMBL6739470 | 0.83 | GRM2 (0.63) | GRM2SMN1; SMN2MMP2MMP9OXTR | |
| SCHEMBL6727582 | 0.82 | BRD4 (0.59) | GRM2BRD4 | |
| SCHEMBL6727625 | 0.82 | GRM2 (0.47) | GRM2BRD4LMNAGAATSHR | |
| SCHEMBL6767469 | 0.82 | GRM2 (0.72) | GRM2 | |
| SCHEMBL6731132 | 0.82 | GRM2 (0.49) | GRM2BRD4LTA4HNR1H2NR1H3 | |
| SCHEMBL6730872 | 0.81 | GRM2 (0.47) | GRM2BRD4LMNAGAATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6800651-B2 | Potentiators of glutamate receptors | ELI LILLY AND COMPANY | 2004-10-05 | — | — | US | claimed |