Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 14/20 | 0.45 |
| ▸ | DAO | P14920 | 2/20 | 0.45 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.44 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.44 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.44 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.41 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | DPP4 | P27487 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13015570 | 0.85 | DAO (0.46) | PARP1DAOADORA3ADORA2AADORA2B | |
| SCHEMBL6766587 | 0.81 | DAO (0.43) | DAOADORA3ADORA2AADORA2BADORA1 | |
| SCHEMBL2084410 | 0.81 | DAO (0.43) | DAOADORA3ADORA2AADORA2BADORA1 | |
| SCHEMBL6768286 | 0.78 | BRD4 (0.44) | PARP1DAOADORA3ADORA2AADORA2B | |
| SCHEMBL13015572 | 0.78 | HPGD (0.46) | — | |
| SCHEMBL306634 | 0.78 | DAO (0.40) | DAOADORA3ADORA2AADORA2BADORA1 | |
| SCHEMBL13015488 | 0.76 | DAO (0.50) | DAOADORA3ADORA2AADORA2BADORA1 | |
| SCHEMBL29502192 | 0.76 | DAO (0.50) | DAOADORA3ADORA2AADORA2BADORA1 | |
| SCHEMBL2082442 | 0.76 | ADORA3 (0.49) | DAOADORA3ADORA2AADORA2BADORA1 | |
| SCHEMBL2084332 | 0.76 | NPSR1 (0.50) | PARP1LMNAPLA2G2AALOX15PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6699880-B1 | STIMULATE MUSCARINIC ACETYLCHOLINE RECEPTORS M4, ANALGESICS | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2004-03-02 | — | — | US | disclosed |
| EP-1221443-A1 | SUBSTITUTED IMIDAZOLIDINONE DERIVATIVES | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2002-07-10 | — | — | EP | disclosed |