Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 2/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.42 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.42 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.42 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.42 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.42 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.42 |
| ▸ | GRIN3A | Q8TCU5 | 2/20 | 0.42 |
| ▸ | ALPL | P05186 | 1/20 | 0.42 |
| ▸ | ALPI | P09923 | 1/20 | 0.42 |
| ▸ | ALPG | P10696 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.38 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6767696 | 0.85 | GAA (0.53) | PKMGAAALDH1A1SMN1; SMN2POLB | |
| SCHEMBL6767993 | 0.83 | GAA (0.54) | PKMGAAALDH1A1SMN1; SMN2POLB | |
| SCHEMBL6763586 | 0.81 | PKM (0.49) | PKMGAAALDH1A1SMN1; SMN2POLB | |
| SCHEMBL5393113 | 0.81 | GAA (0.59) | PKMGAAALDH1A1SMN1; SMN2POLB | |
| SCHEMBL13303940 | 0.80 | GAA (0.68) | PKMGAAALDH1A1SMN1; SMN2POLB | |
| SCHEMBL6763542 | 0.79 | PKM (0.50) | PKMGAAALDH1A1SMN1; SMN2POLB | |
| SCHEMBL2056376 | 0.77 | GAA (0.63) | PKMGAAALDH1A1SMN1; SMN2POLB | |
| SCHEMBL1824734 | 0.77 | GAA (0.54) | PKMGAAALDH1A1SMN1; SMN2POLB | |
| SCHEMBL13015140 | 0.75 | GAA (0.53) | PKMGAAALDH1A1SMN1; SMN2POLB | |
| SCHEMBL6767844 | 0.75 | GAA (0.56) | PKMGAAALDH1A1SMN1; SMN2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6699880-B1 | STIMULATE MUSCARINIC ACETYLCHOLINE RECEPTORS M4, ANALGESICS | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2004-03-02 | — | — | US | disclosed |
| EP-1221443-A1 | SUBSTITUTED IMIDAZOLIDINONE DERIVATIVES | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2002-07-10 | — | — | EP | disclosed |