SCHEMBL6766949

SCHEMBL6766949

CN(Cc1ccc(C2=NCCN2)cc1)C(=O)CNC(=O)CN(C)S(=O)(=O)c1cccc2ccccc12

nearest known ligand 0.68

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
BDKRB1 P46663 15/20 0.68
ALDH1A1 P00352 2/20 0.44
MEN1 O00255 1/20 0.44
KMT2A Q03164 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6759970 0.88 BDKRB1 (0.78) BDKRB1
SCHEMBL6766954 0.87 BDKRB1 (0.51) BDKRB1ALDH1A1
SCHEMBL6762292 0.85 BDKRB1 (0.64) BDKRB1MEN1KMT2A
SCHEMBL4036143 0.84 BDKRB1 (0.65) BDKRB1
SCHEMBL6763217 0.84 BDKRB1 (0.73) BDKRB1
SCHEMBL4033835 0.83 BDKRB1 (0.77) BDKRB1
SCHEMBL6764342 0.82 BDKRB1 (0.88) BDKRB1KMT2A
SCHEMBL6759993 0.82 BDKRB1 (0.78) BDKRB1KMT2A
SCHEMBL6760002 0.81 BDKRB1 (1.00) BDKRB1KMT2A
SCHEMBL5110344 0.81 BDKRB1 (0.68) BDKRB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20040063725-A1 Novel n(phenylsulphonyl)glycine derivatives and their therapeutic use LABORATORIES FOURNIER S.A. (FR) 2004-04-01 US disclosed
EP-1351928-A2 NOVEL N(PHENYLSULPHONYL)GLYCINE DERIVATIVES AND THEIR THERAPEUTIC USE LABORATOIRES FOURNIER S.A. (FR) 2003-10-15 EP disclosed
WO-2002053516-A2 N(PHENYLSULPHONYL)GLYCINE DERIVATIVES AND THEIR THERAPEUTIC USE LABORATOIRES FOURNIER SA (FR) 2002-07-11 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040063725-A1 Novel n(phenylsulphonyl)glycine derivatives and their therapeutic use GLS, GLS2, GLRB BDKRB1 481/4885ALDH1A1 2730/4885MEN1 3527/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.