Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | MPO | P05164 | 1/20 | 0.48 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.48 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | LTA4H | P09960 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 1/20 | 0.45 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.45 |
| ▸ | PLOD2 | O00469 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2196 | 0.97 | — | — | |
| SCHEMBL8016216 | 0.97 | NAPRT (0.59) | NAPRTALDH1A1MEN1KMT2ACYP1A2 | |
| Hydrochloric Acid SCHEMBL7300524 | 0.95 | NAPRT (0.56) | NAPRTALDH1A1MEN1KMT2ACYP1A2 | |
| Hydrochloric Acid SCHEMBL26328 | 0.95 | NAPRT (0.56) | NAPRTALDH1A1MEN1KMT2ACYP1A2 | |
| Hydrochloric Acid SCHEMBL28289025 | 0.84 | NAPRT (0.46) | NAPRTALDH1A1MEN1KMT2ACYP1A2 | |
| SCHEMBL6300124 | 0.83 | HDAC1 (0.59) | NAPRTALDH1A1KDM4ELTA4HLMNA | |
| Benzoyl Chloride SCHEMBL587072 | 0.78 | KMT2A (0.56) | NAPRTALDH1A1MEN1KMT2ACYP1A2 | |
| SCHEMBL7461375 | 0.78 | GAA (0.79) | ALDH1A1MEN1KMT2AKDM4EGAA | |
| SCHEMBL25202703 | 0.78 | HDAC1 (0.65) | NAPRTALDH1A1MEN1KMT2ACYP1A2 | |
| SCHEMBL19084903 | 0.78 | HDAC1 (0.65) | NAPRTALDH1A1MEN1KMT2ACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118204105-B | Preparation method of desulfurization catalyst | 烟台百川汇通科技有限公司 | 2024-07-16 | — | — | CN | disclosed |
| CN-118204105-A | Preparation method of desulfurization catalyst | 烟台百川汇通科技有限公司 | 2024-06-18 | — | — | CN | disclosed |
| CN-112279888-B | Polypeptide inhibitor of APC/Asef interaction and application thereof | 上海交通大学医学院 | 2022-09-13 | — | — | CN | disclosed |
| US-6716856-B1 | CELL PROLIFERATIVE DISORDERS OR ALZHEIMER'S DISEASE; REDUCED TOXICITY; CDK/CYCLIN KINASE INHIBITORY ACTIVITY | PHARMACIA & TUBJOHN SPA (IT) | 2004-04-06 | — | — | US | disclosed |