Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 5/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 6/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.39 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.39 |
| ▸ | TUBB4A | P04350 | 3/20 | 0.38 |
| ▸ | TUBB | P07437 | 3/20 | 0.38 |
| ▸ | TUBA3C | P0DPH7 | 3/20 | 0.38 |
| ▸ | TUBA1B | P68363 | 3/20 | 0.38 |
| ▸ | TUBA4A | P68366 | 3/20 | 0.38 |
| ▸ | TUBB4B | P68371 | 3/20 | 0.38 |
| ▸ | TUBB3 | Q13509 | 3/20 | 0.38 |
| ▸ | TUBB2A | Q13885 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6769000 | 0.81 | CYP1A1 (0.42) | TP53MAPTSMN1; SMN2NPC1RAB9A | |
| SCHEMBL6767402 | 0.77 | MAPT (0.47) | TP53POLBMAPTSMN1; SMN2NPC1 | |
| SCHEMBL10130871 | 0.75 | TP53 (0.46) | TP53POLBMAPTSMN1; SMN2NPC1 | |
| SCHEMBL14421030 | 0.74 | GAA (0.51) | TP53POLBMAPTSMN1; SMN2NPC1 | |
| SCHEMBL10162219 | 0.73 | TP53 (0.47) | TP53POLBMAPTSMN1; SMN2NPC1 | |
| SCHEMBL6769163 | 0.72 | RAB9A (0.46) | TP53MAPTSMN1; SMN2NPC1RAB9A | |
| SCHEMBL6767117 | 0.70 | MAPT (0.43) | TP53POLBMAPTSMN1; SMN2NPC1 | |
| SCHEMBL12299897 | 0.69 | SMN1; SMN2 (0.50) | TP53SMN1; SMN2NPC1RAB9AKDM4E | |
| SCHEMBL6774258 | 0.69 | SMN1; SMN2 (0.40) | TP53MAPTSMN1; SMN2NPC1RAB9A | |
| SCHEMBL6769075 | 0.69 | SMN1; SMN2 (0.40) | TP53POLBMAPTSMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6723724-B2 | PSYCHOLOGICAL DISORDERS | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2004-04-20 | — | — | US | disclosed |