Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 2/20 | 0.34 |
| ▸ | CES1 | P23141 | 2/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | CES2 | O00748 | 1/20 | 0.34 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.33 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.33 |
| ▸ | MMP9 | P14780 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | ARG2 | P78540 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5968611 | 0.76 | MAOB (0.40) | TSHRMAOBCALM1TDP1IDO1 | |
| SCHEMBL1440051 | 0.76 | IDO1 (0.42) | TSHRMAOBCALM1TDP1IDO1 | |
| Fluoride SCHEMBL27912819 | 0.74 | IDO1 (0.40) | TSHRMAOBCALM1TDP1IDO1 | |
| SCHEMBL27912795 | 0.74 | GAA (0.36) | TSHRMAOBCALM1TDP1IDO1 | |
| SCHEMBL296775 | 0.73 | MAOB (0.37) | TSHRMAOBCALM1TDP1IDO1 | |
| SCHEMBL16594343 | 0.73 | TP53 (0.39) | TSHRMAOBCALM1TDP1IDO1 | |
| SCHEMBL2347873 | 0.73 | LOXL2 (0.39) | TSHRMAOBCALM1IDO1ALDH1A1 | |
| SCHEMBL3693359 | 0.73 | MAOB (0.37) | TSHRMAOBCALM1IDO1CES1 | |
| SCHEMBL819896 | 0.72 | TSHR (0.48) | TSHRMAOBCALM1TDP1IDO1 | |
| SCHEMBL3237076 | 0.72 | TSHR (0.48) | TSHRMAOBCALM1TDP1IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 174 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7347970-B2 | Biocides based on silanol terminated silanes and siloxanes | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2008-03-25 | — | — | US | claimed |
| US-20060194764-A1 | Biocides based on silanol terminated silanes and siloxanes | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. | 2006-08-31 | — | — | US | claimed |
| WO-2006028491-A1 | BIOCIDES BASED ON SILANOL TERMINATED SILANES AND SILOXANES | UNIVERSITY OF FLORIDA (US) | 2006-03-16 | — | — | WO | claimed |
| US-4592928-A | Coating with a peroxide curable polysiloxane elastomer; heating to cure | DOW CORNING CORPORATION (US) | 1986-06-03 | — | — | US | claimed |
| US-4026835-A | Method of preparing heat cured siloxane foams using rhodium catalyst and foams prepared therefrom | DOW CORNING CORPORATION (US) | 1977-05-31 | — | — | US | claimed |
| US-4026842-A | ORGANO-HYDROGEN SILOXANES | DOW CORNING CORPORATION (US) | 1977-05-31 | — | — | US | claimed |
| WO-2024088062-A1 | THERMALLY-CONDUCTIVE ADDITION TYPE ORGANOSILICON COMPOSITION FOR POTTING | 江西蓝星星火有机硅有限公司 | 2024-05-02 | — | — | WO | disclosed |
| WO-2024067506-A1 | METHOD FOR POST-TREATING AN OBJECT | ELKEM SILICONES SHANGHAI CO., LTD. (CN) | 2024-04-04 | — | — | WO | disclosed |
| CN-115612446-B | Heat-conducting addition type organic silicon composition for encapsulation | 江西蓝星星火有机硅有限公司 | 2024-01-26 | — | — | CN | disclosed |
| CN-117106307-A | Curable silicone composition with good flame retardancy | 埃肯有机硅（上海）有限公司 | 2023-11-24 | — | — | CN | disclosed |
| CN-113518800-B | Curable silicone composition with good flame retardancy | 埃肯有机硅（上海）有限公司 | 2023-09-15 | — | — | CN | disclosed |
| US-20230276880-A1 | Protective Garment Having Water and Oil Resistance | BURLINGTON INDUSTRIES LLC | 2023-09-07 | — | — | US | disclosed |
| WO-2023167976-A2 | PROTECTIVE GARMENT HAVING WATER AND OIL RESISTANCE | BURLINGTON INDUSTRIES LLC (US) | 2023-09-07 | — | — | WO | disclosed |
| US-4163081-A | POLYSILOXANES ENDCAPPED WITH VINYL-CONTAINING GROUP, AMIDOSILOXANE | DOW CORNING CORPORATION (US) | 1979-07-31 | — | — | US | disclosed |
| US-4116919-A | SILAZANES | DOW CORNING CORPORATION (US) | 1978-09-26 | — | — | US | disclosed |
| US-4052357-A | SILICA FILLER, BLAST FURNACE SLAG FIBER | DOW CORNING CORPORATION (US) | 1977-10-04 | — | — | US | disclosed |
| US-3989667-A | POLYSILOXANES | DOW CORNING CORPORATION (US) | 1976-11-02 | — | — | US | disclosed |
| US-3971818-A | PLATINUM CATALYST, GAS LIQUID CHROMATOGRAPHY | DOW CORNING CORPORATION (US) | 1976-07-27 | — | — | US | disclosed |
| US-3933880-A | ACETYLENIC ALCOHOL WITH A SILOXANE COMPOUND | DOW CORNING CORPORATION (US) | 1976-01-20 | — | — | US | disclosed |
| US-3933882-A | ACETYLENIC ALCOHOL WITH A SILOXANE COMPOUND | DOW CORNING CORPORATION (US) | 1976-01-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060194764-A1 | Biocides based on silanol terminated silanes and siloxanes | MSR1, S1PR3, TAS2R3 | TSHR 438/4885MAOB 4048/4885CALM1 4166/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.