Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 10/20 | 0.52 |
| ▸ | CARM1 | Q86X55 | 2/20 | 0.39 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 5/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6763634 | 0.93 | GRM2 (0.52) | GRM2CARM1PRMT6BRD4SLC6A4 | |
| SCHEMBL6730757 | 0.89 | BRD4 (0.48) | GRM2CARM1PRMT6BRD4SLC6A4 | |
| SCHEMBL6738614 | 0.86 | GRM2 (0.52) | GRM2BRD4 | |
| SCHEMBL6727716 | 0.84 | GRM2 (0.73) | GRM2BRD4 | |
| SCHEMBL6768039 | 0.82 | BRD4 (0.47) | GRM2CARM1PRMT6BRD4SLC6A4 | |
| SCHEMBL6772754 | 0.81 | GRM2 (0.57) | GRM2BRD4 | |
| SCHEMBL6766185 | 0.81 | GRM2 (0.54) | GRM2BRD4 | |
| SCHEMBL6732988 | 0.77 | GRM2 (0.52) | GRM2 | |
| SCHEMBL6735363 | 0.76 | GRM2 (0.68) | GRM2 | |
| SCHEMBL6738900 | 0.76 | GRM2 (0.68) | GRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6800651-B2 | Potentiators of glutamate receptors | ELI LILLY AND COMPANY | 2004-10-05 | — | — | US | claimed |