Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 13/20 | 0.47 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.44 |
| ▸ | CARM1 | Q86X55 | 2/20 | 0.42 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6730757 | 0.93 | BRD4 (0.48) | BRD4GRM2CARM1PRMT6SLC6A4 | |
| SCHEMBL6763634 | 0.91 | GRM2 (0.52) | BRD4GRM2CARM1PRMT6SLC6A4 | |
| SCHEMBL6727582 | 0.85 | BRD4 (0.59) | BRD4GRM2 | |
| SCHEMBL6767693 | 0.82 | GRM2 (0.52) | BRD4GRM2CARM1PRMT6SLC6A4 | |
| SCHEMBL6736489 | 0.82 | GRM2 (0.69) | BRD4GRM2 | |
| SCHEMBL6767846 | 0.82 | BRD4 (0.50) | BRD4GRM2 | |
| SCHEMBL6766864 | 0.79 | BRD4 (0.49) | BRD4GRM2 | |
| SCHEMBL6738658 | 0.78 | GRM2 (0.62) | BRD4GRM2 | |
| SCHEMBL6730770 | 0.75 | GRM2 (0.67) | BRD4GRM2 | |
| SCHEMBL6738614 | 0.74 | GRM2 (0.52) | BRD4GRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6800651-B2 | Potentiators of glutamate receptors | ELI LILLY AND COMPANY | 2004-10-05 | — | — | US | claimed |