Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.60 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | DRD2 | P14416 | 5/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | DRD1 | P21728 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | PDE3B | Q13370 | 3/20 | 0.48 |
| ▸ | PDE3A | Q14432 | 3/20 | 0.48 |
| ▸ | P2RY12 | Q9H244 | 2/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA6 | P23280 | 1/20 | 0.46 |
| ▸ | CA5A | P35218 | 1/20 | 0.46 |
| ▸ | CA7 | P43166 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15932952 | 0.93 | MAPT (0.60) | MAPTESR2HSD17B10ALDH1A1HPGD | |
| SCHEMBL3232045 | 0.86 | HSD17B10 (0.80) | MAPTESR2HSD17B10ALDH1A1HPGD | |
| SCHEMBL7031273 | 0.84 | MAPT (0.46) | MAPTESR2HSD17B10ALDH1A1HPGD | |
| SCHEMBL7031638 | 0.84 | PDE3B (0.54) | MAPTESR2HSD17B10ALDH1A1HPGD | |
| SCHEMBL28890755 | 0.83 | HPGD (0.75) | MAPTESR2HSD17B10ALDH1A1HPGD | |
| SCHEMBL7406783 | 0.83 | MAPT (0.51) | MAPTESR2HSD17B10ALDH1A1HPGD | |
| SCHEMBL12321247 | 0.83 | MAPT (0.51) | MAPTESR2HSD17B10ALDH1A1HPGD | |
| SCHEMBL252370 | 0.81 | DRD2 (0.50) | MAPTESR2HSD17B10ALDH1A1HPGD | |
| SCHEMBL3400442 | 0.80 | DRD2 (0.49) | MAPTESR2HSD17B10DRD2DRD1 | |
| SCHEMBL7039556 | 0.78 | PDE3B (0.57) | MAPTESR2HSD17B10ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6699880-B1 | STIMULATE MUSCARINIC ACETYLCHOLINE RECEPTORS M4, ANALGESICS | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2004-03-02 | — | — | US | disclosed |
| EP-1221443-A1 | SUBSTITUTED IMIDAZOLIDINONE DERIVATIVES | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2002-07-10 | — | — | EP | disclosed |