Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5555508 | 0.73 | SMN1; SMN2 (1.00) | SMN1; SMN2KMT2AALDH1A1PKMMEN1 | |
| SCHEMBL14472639 | 0.72 | ALDH1A1 (0.46) | SMN1; SMN2KMT2AALDH1A1MEN1 | |
| SCHEMBL17912458 | 0.72 | SMN1; SMN2 (0.76) | SMN1; SMN2KMT2AALDH1A1PKMMEN1 | |
| SCHEMBL9508073 | 0.70 | — | — | |
| SCHEMBL9366843 | 0.64 | ALDH1A1 (0.32) | ALDH1A1 | |
| SCHEMBL13735003 | 0.63 | ALDH1A1 (0.40) | SMN1; SMN2KMT2AALDH1A1PKMHTT | |
| SCHEMBL9702514 | 0.62 | MAPT (0.37) | SMN1; SMN2KMT2AALDH1A1PKMHTT | |
| SCHEMBL14472642 | 0.61 | ALDH1A1 (0.39) | SMN1; SMN2KMT2AALDH1A1MEN1 | |
| SCHEMBL11776433 | 0.58 | MAPT (0.43) | SMN1; SMN2KMT2AALDH1A1PKMHTT | |
| SCHEMBL6302472 | 0.58 | HTT (0.53) | SMN1; SMN2KMT2AALDH1A1PKMHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6716843-B2 | INHIBITOR OF DIPEPTIDYL-PEPTIDASE IV | LES LABORATOIRES SERVIER (FR) | 2004-04-06 | — | — | US | disclosed |
| US-20030087950-A1 | New alpha-amino acid sulphonyl compounds | LES LABORATOIRES SERVIER (FR) | 2003-05-08 | — | — | US | disclosed |
| EP-1245568-A1 | Sulfonyl derivatives of amino acids and their use as inhibitors of dipeptidyl-peptidase IV (DPP IV) | Les Laboratoires Servier (FR) | 2002-10-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030087950-A1 | New alpha-amino acid sulphonyl compounds | DNPEP, DPP4, DPP7 | SMN1; SMN2 3143/4885KMT2A 1302/4885ALDH1A1 191/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.