Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | WDR5 | P61964 | 3/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | BRS3 | P32247 | 2/20 | 0.40 |
| ▸ | ATP1A1 | P05023 | 2/20 | 0.40 |
| ▸ | ATP1B1 | P05026 | 2/20 | 0.40 |
| ▸ | ATP1A3 | P13637 | 2/20 | 0.40 |
| ▸ | ATP1B2 | P14415 | 2/20 | 0.40 |
| ▸ | ATP4A | P20648 | 2/20 | 0.40 |
| ▸ | ATP1A2 | P50993 | 2/20 | 0.40 |
| ▸ | ATP4B | P51164 | 2/20 | 0.40 |
| ▸ | ATP1B3 | P54709 | 2/20 | 0.40 |
| ▸ | FXYD2 | P54710 | 2/20 | 0.40 |
| ▸ | ATP1A4 | Q13733 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.40 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6772040 | 1.00 | KMT2A (0.41) | KMT2AMEN1WDR5CYP2C9BRS3 | |
| SCHEMBL6771448 | 0.93 | KMT2A (0.43) | KMT2AMEN1WDR5CYP2C9BRS3 | |
| SCHEMBL6773081 | 0.93 | KMT2A (0.43) | KMT2AMEN1WDR5CYP2C9BRS3 | |
| SCHEMBL6777277 | 0.88 | KMT2A (0.36) | KMT2AMEN1WDR5CYP2C9BRS3 | |
| SCHEMBL29474363 | 0.86 | KMT2A (0.43) | KMT2AMEN1WDR5CYP2C9BRS3 | |
| SCHEMBL7844981 | 0.86 | KMT2A (0.43) | KMT2AMEN1WDR5CYP2C9BRS3 | |
| SCHEMBL10512130 | 0.85 | KMT2A (0.41) | KMT2AMEN1WDR5CYP2C9BRS3 | |
| SCHEMBL16349245 | 0.85 | TDP1 (0.38) | ATP1A1ATP1B1ATP1A3ATP1B2ATP4A | |
| SCHEMBL9264132 | 0.85 | KMT2A (0.40) | KMT2AMEN1WDR5CYP2C9BRS3 | |
| SCHEMBL7841182 | 0.84 | KMT2A (0.42) | KMT2AMEN1WDR5CYP2C9BRS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6673819-B2 | NITRIC OXIDE RELEASING COMPOUND | ASTRAZENECA AB (SE) | 2004-01-06 | — | — | US | claimed |