Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 11/20 | 0.54 |
| ▸ | LTA4H | P09960 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.37 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.35 |
| ▸ | MMP2 | P08253 | 1/20 | 0.35 |
| ▸ | MMP9 | P14780 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6763463 | 0.91 | GRM2 (0.46) | GRM2LTA4HPTGS2LMNAGAA | |
| SCHEMBL6732387 | 0.89 | GRM2 (0.47) | GRM2BRD4 | |
| SCHEMBL6739586 | 0.88 | GRM2 (0.69) | GRM2LMNAGAATSHRHTT | |
| SCHEMBL6731093 | 0.87 | GRM2 (0.52) | GRM2SMN1; SMN2MMP2MMP9 | |
| SCHEMBL6731292 | 0.86 | GRM2 (0.57) | GRM2LMNAGAATSHRHTT | |
| SCHEMBL6738614 | 0.85 | GRM2 (0.52) | GRM2BRD4 | |
| SCHEMBL6766550 | 0.84 | GRM2 (0.62) | GRM2LPAR1LPAR5 | |
| SCHEMBL6728253 | 0.84 | GRM2 (0.49) | GRM2MMP2MMP9 | |
| SCHEMBL7419860 | 0.84 | GRM2 (0.49) | GRM2LTA4HPTGS2MMP2MMP9 | |
| SCHEMBL6727570 | 0.84 | GRM2 (0.59) | GRM2LMNAGAATSHRHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6800651-B2 | Potentiators of glutamate receptors | ELI LILLY AND COMPANY | 2004-10-05 | — | — | US | claimed |