Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | HRH1 | P35367 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | JAK2 | O60674 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7889403 | 0.92 | MAPK1 (0.51) | KDM4EMAPK1MEN1KMT2AMAPT | |
| SCHEMBL17445915 | 0.90 | KDM4E (0.51) | KDM4EMAPK1MEN1KMT2AMAPT | |
| SCHEMBL27946664 | 0.87 | KDM4E (0.57) | KDM4EMAPK1MEN1KMT2AMAPT | |
| SCHEMBL18974135 | 0.83 | HRH1 (0.51) | MAPTL3MBTL1NPSR1HRH1HPGD | |
| SCHEMBL7873203 | 0.83 | IDO1 (0.53) | KDM4EMAPK1MEN1KMT2AMAPT | |
| SCHEMBL561327 | 0.82 | CYP1A2 (0.56) | KDM4EMAPK1MEN1KMT2AMAPT | |
| SCHEMBL11212429 | 0.82 | HTR1B (0.58) | KDM4EMAPK1MEN1KMT2AMAPT | |
| SCHEMBL7997617 | 0.82 | PDCD1 (0.43) | KDM4EMAPK1MEN1KMT2AMAPT | |
| SCHEMBL2806322 | 0.81 | L3MBTL1 (0.50) | KDM4EMAPK1MEN1KMT2AMAPT | |
| SCHEMBL6267357 | 0.81 | MAPT (0.53) | KDM4EMAPK1MEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6787538-B2 | HORMONE REPLACEMENT THERAPY; AGONISTS, ANTAGONISTS; ANTIESTROGENS WITH LITTLE TO NO INTRINSIC ESTROGENICITY | WYETH | 2004-09-07 | — | — | US | disclosed |