Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.38 |
| ▸ | NAMPT | P43490 | 1/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.37 |
| ▸ | DHPS | P49366 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6770009 | 1.00 | HTT (0.40) | HTTALDH1A1TSHRLMNANAPRT | |
| SCHEMBL6766324 | 0.86 | TSHR (0.42) | HTTALDH1A1TSHRLMNANAPRT | |
| SCHEMBL6766329 | 0.86 | TSHR (0.42) | HTTALDH1A1TSHRLMNANAPRT | |
| SCHEMBL6776347 | 0.83 | ALDH1A1 (0.45) | HTTALDH1A1TSHRLMNANAPRT | |
| SCHEMBL6776344 | 0.83 | ALDH1A1 (0.45) | HTTALDH1A1TSHRLMNANAPRT | |
| SCHEMBL6770252 | 0.83 | ALDH1A1 (0.47) | HTTALDH1A1TSHRLMNAL3MBTL1 | |
| SCHEMBL6770251 | 0.83 | ALDH1A1 (0.47) | HTTALDH1A1TSHRLMNAL3MBTL1 | |
| SCHEMBL6770706 | 0.78 | ALDH1A1 (0.50) | ALDH1A1TSHRLMNAL3MBTL1TYRO3 | |
| SCHEMBL6770707 | 0.78 | ALDH1A1 (0.50) | ALDH1A1TSHRLMNAL3MBTL1TYRO3 | |
| SCHEMBL6777804 | 0.77 | ALDH1A1 (0.50) | HTTALDH1A1TSHRLMNANAPRT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6716857-B2 | 1-(3-HYDROCARBYLOXYIMINO-3-(1-ALKYL-1,2,5,6-TETRAHYDROPYRID-3-YL) -ALKYLPYRROLIDIN-2-ONE DERIVATIVES; RECEPTIVITY; ANALGESICS, GLAUCOMA, PSYCHOSIS, SCHIZOPHRENIA, ANXIOLYTIC AGENTS, BIPOLAR DISORDERS; ANTIDEPRESSANTS; SLEEP DISORDERS | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2004-04-06 | — | — | US | claimed |
| US-20030119880-A1 | Tetrahydropyridine derivatives acting on muscarinic acetylcholine receptors | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2003-06-26 | — | — | US | claimed |
| US-6716857-B2 | 1-(3-HYDROCARBYLOXYIMINO-3-(1-ALKYL-1,2,5,6-TETRAHYDROPYRID-3-YL) -ALKYLPYRROLIDIN-2-ONE DERIVATIVES; RECEPTIVITY; ANALGESICS, GLAUCOMA, PSYCHOSIS, SCHIZOPHRENIA, ANXIOLYTIC AGENTS, BIPOLAR DISORDERS; ANTIDEPRESSANTS; SLEEP DISORDERS | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2004-04-06 | — | — | US | disclosed |
| US-20030119880-A1 | Tetrahydropyridine derivatives acting on muscarinic acetylcholine receptors | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2003-06-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030119880-A1 | Tetrahydropyridine derivatives acting on muscarinic acetylcholine receptors | CHRM1, CHRM3, CHRM2 | HTT 3679/4885ALDH1A1 596/4885TSHR 92/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.