Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CAPN1 | P07384 | 16/20 | 0.39 |
| ▸ | CTSB | P07858 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5680250 | 0.70 | PTGS1 (0.54) | CAPN1 | |
| SCHEMBL2369340 | 0.66 | CAPN1 (0.61) | CAPN1CTSB | |
| SCHEMBL3292711 | 0.66 | CAPN1 (0.61) | CAPN1CTSB | |
| SCHEMBL17865652 | 0.66 | CAPN1 (0.61) | CAPN1CTSB | |
| SCHEMBL10705687 | 0.65 | — | — | |
| SCHEMBL2266848 | 0.63 | CAPN1 (0.58) | CAPN1CTSB | |
| SCHEMBL2269431 | 0.63 | CAPN1 (0.58) | CAPN1CTSB | |
| SCHEMBL5563236 | 0.63 | CAPN1 (0.58) | CAPN1CTSB | |
| SCHEMBL24862871 | 0.62 | CAPN1 (0.73) | CAPN1CTSB | |
| SCHEMBL5491360 | 0.61 | CAPN1 (0.53) | CAPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6747024-B1 | INHIBITING CALPAIN AND/OR REACTIVE OXYGEN SPECIES IN WARM-BLOODED ANIMALS | SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES (S.C.R.A.S.) (FR) | 2004-06-08 | — | — | US | disclosed |