Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.64 |
| ▸ | NAMPT | P43490 | 1/20 | 0.54 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | RARB | P10826 | 2/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.49 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.49 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.49 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | PPARA | Q07869 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL3896488 | 0.98 | NAPRT (0.61) | NAPRTNAMPTTBXAS1ALDH1A1RARB | |
| SCHEMBL10638830 | 0.92 | NAPRT (0.59) | NAPRTNAMPTTBXAS1ALDH1A1RARB | |
| SCHEMBL5350293 | 0.92 | NAPRT (0.59) | NAPRTNAMPTTBXAS1ALDH1A1RARB | |
| SCHEMBL18906031 | 0.88 | HDAC1 (0.65) | NAPRTNAMPTALDH1A1HDAC6HDAC1 | |
| SCHEMBL70166 | 0.87 | TSHR (0.67) | NAPRTALDH1A1RARBHDAC1TP53 | |
| Terephthalic Acid SCHEMBL4612225 | 0.87 | TSHR (0.67) | NAPRTALDH1A1RARBHDAC1TP53 | |
| Hydrochloric Acid SCHEMBL7132238 | 0.84 | TSHR (0.63) | NAPRTALDH1A1RARBHDAC1TP53 | |
| SCHEMBL10639390 | 0.82 | NAPRT (0.57) | NAPRTNAMPTTBXAS1ALDH1A1HDAC6 | |
| SCHEMBL10639379 | 0.82 | NAPRT (0.57) | NAPRTNAMPTTBXAS1ALDH1A1HDAC6 | |
| SCHEMBL27536266 | 0.82 | CYP17A1 (0.71) | HDAC6HDAC1HDAC2HDAC8CYP17A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6825181-B1 | ORALLY ADMINISTRATED TO EXHIBIT A STRONG ANTICOAGULANT EFFECT BY INHIBITING ACTIVATED BLOOD- COAGULATION FACTOR X | AJINOMOTO CO., INC. (JP) | 2004-11-30 | — | — | US | disclosed |
| CN-1302292-A | Aminoisoquinoline derivatives | AJINOMOTO KK (JP) | 2001-07-04 | — | — | CN | disclosed |
| EP-1065200-A1 | AMINOISOQUINOLINE DERIVATIVES | Ajinomoto Co., Inc. (JP) | 2001-01-03 | — | — | EP | disclosed |