SCHEMBL676984

SCHEMBL676984

O=C([O-])C1(C(=O)[O-])CCC1.[Pt+2]

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ammonia Solution, Strong SCHEMBL1450443 0.97
SCHEMBL2671352 0.94
SCHEMBL9498015 0.94
SCHEMBL10338084 0.94
SCHEMBL5367506 0.94 CA4 (0.33)
SCHEMBL9619101 0.94
Silver SCHEMBL3907380 0.94
Potassium Ion SCHEMBL3280844 0.94 CA4 (0.33)
SCHEMBL3907387 0.94
SCHEMBL30418339 0.94

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 64 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20140288077-A1 SUBSTITUTED 4-PHENOXYPHENOL ANALOGS AS MODULATORS OF PROLIFERATING CELL NUCLEAR ANTIGEN ACTIVITY ST. JUDE CHILDREN'S RESEARCH HOSPITAL (US) 2014-09-25 US claimed
WO-2013006734-A1 SUBSTITUTED 4-PHENOXYPHENOL ANALOGS AS MODULATORS OF PROLIFERATING CELL NUCLEAR ANTIGEN ACTIVITY ST. JUDE CHILDREN'S RESEARCH HOSPITAL (US) 2013-01-10 WO claimed
EP-0201804-B1 COMPOSITION TO TREATING BONE DISORDERS Sloan-Kettering Institute For Cancer Research (US) 1992-07-01 EP claimed
US-4686104-A GERMANIUM OR PLATINUM COMPOUNDS TO DECREASE CALCIUM LOSS SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) 1987-08-11 US claimed
EP-0201804-A1 Composition to treating bone disorders Sloan-Kettering Institute For Cancer Research (US) 1986-11-20 EP claimed
US-20240189409-A1 Personalized Site-Specific Immunomodulation QU BIOLOGICS INC. (CA) 2024-06-13 US disclosed
EP-4324526-A2 IMMUNOGENIC ANTI-INFLAMMATORY COMPOSITIONS Qu Biologics Inc. (CA) 2024-02-21 EP disclosed
US-11679111-B2 Fatty acid synthase inhibitors DUKE UNIVERSITY (US) 2023-06-20 US disclosed
US-11642362-B2 Methods of inhibiting cell proliferation and METTL8 activity NATIONAL UNIVERSITY OF SINGAPORE (SG) 2023-05-09 US disclosed
CN-109790191-B Platinum complexes and methods of use thereof 香港大学 2022-04-08 CN disclosed
US-20200222444-A1 METHODS OF INHIBITING CELL PROLIFERATION AND METTL8 ACTIVITY NATIONAL UNIVERSITY OF SINGAPORE (SG) 2020-07-16 US disclosed
EP-3649242-A2 METHODS OF INHIBITING CELL PROLIFERATION AND METTL8 ACTIVITY National University of Singapore (SG) 2020-05-13 EP disclosed
US-20060089341-A1 Protein-bound derivatives of platinum complexes containing cyclobutane1,1-dicarboxyllate ligands KTB TUMORFORSCHUNGS GMBH (DE) 2006-04-27 US disclosed
US-20040258770-A1 Use of 4-pyridylmethylphthalazines for cancer treatment DUGAN MARGARET HAN (US) 2004-12-23 US disclosed
US-20040258771-A1 Reduced toxicity cisplatin formulations and methods for using the same TOSK, INC. 2004-12-23 US disclosed
US-20040235796-A1 Combinations comprising epothilones and pharmaceutical uses thereof NOVARTIS AG (CH) 2004-11-25 US disclosed
US-20030082102-A1 Radioactive platinum complexes for cancer treatment ORDER, STANLEY E., MD PC D/B/A CENTER FOR MOLECULAR MEDICINE 2003-05-01 US disclosed
US-5877215-A Method of treating neoplastic cells with prostaglandin and radiation treatment or prostaglandin and platinum-based anti-tumor agents MEDICAL UNIVERSITY OF SOUTH CAROLINA (US) 1999-03-02 US disclosed
US-5620703-A LIPOSOME-ENCAPSULATED ANTITUMOR,-CARCINOGENIC AGENTS; VIRICIDES; LEUKOPENIA MAX-DELBRUCK-CENTRUM FUR MOLEKULARE MEDIZIN (DE) 1997-04-15 US disclosed
EP-0201804-B1 COMPOSITION TO TREATING BONE DISORDERS Sloan-Kettering Institute For Cancer Research (US) 1992-07-01 EP disclosed