⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10338084 | 0.94 | — | — | |
| SCHEMBL676984 | 0.94 | — | — | |
| SCHEMBL9498015 | 0.94 | — | — | |
| Silver SCHEMBL3907380 | 0.94 | — | — | |
| SCHEMBL5367506 | 0.94 | CA4 (0.33) | — | |
| SCHEMBL28968474 | 0.94 | — | — | |
| SCHEMBL3907387 | 0.94 | — | — | |
| Potassium Ion SCHEMBL3280844 | 0.94 | CA4 (0.33) | — | |
| SCHEMBL2671352 | 0.94 | — | — | |
| SCHEMBL30418339 | 0.94 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0215393-B1 | PLATINUM(II) COMPLEXES OF 1,1-CYCLOBUTANE-DICARBOXYLATE, A PROCESS FOR PREPARING THEM AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | FERRER INTERNACIONAL, S.A. (ES) | 1990-11-28 | — | — | EP | claimed |
| EP-0215393-A2 | Platinum(II) complexes of 1,1-cyclobutane-dicarboxylate, a process for preparing them and pharmaceutical compositions containing them | FERRER INTERNACIONAL, S.A. (ES) | 1987-03-25 | — | — | EP | claimed |
| CN-115785162-A | Separating and purifying intermediate containing dihydrate platinum fragment and preparing platinum anticancer drug or [ Pt (NH) 3 ) 4 ] 2+ Method | 云南贵金属实验室有限公司 | 2023-03-14 | — | — | CN | disclosed |
| US-5132323-A | Treatment of animals | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 1992-07-21 | — | — | US | disclosed |
| EP-0333756-B1 | 1,2-DIAMINOCYCLOHEXANE-PLATINUM COMPLEXES WITH ANTITUMOR ACTIVITY | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 1992-01-15 | — | — | EP | disclosed |
| US-5011959-A | 1,2-diaminocyclohexane-platinum complexes with antitumor activity | THE BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 1991-04-30 | — | — | US | disclosed |
| US-4994591-A | Antitumor, anticarcinogenic agents | THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NY (US) | 1991-02-19 | — | — | US | disclosed |
| EP-0215393-B1 | PLATINUM(II) COMPLEXES OF 1,1-CYCLOBUTANE-DICARBOXYLATE, A PROCESS FOR PREPARING THEM AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | FERRER INTERNACIONAL, S.A. (ES) | 1990-11-28 | — | — | EP | disclosed |
| EP-0333756-A1 | 1,2-DIAMINOCYCLOHEXANE-PLATINUM COMPLEXES WITH ANTITUMOR ACTIVITY. | UNIV TEXAS (US) | 1989-09-27 | — | — | EP | disclosed |
| WO-1988003925-A1 | 1,2-DIAMINOCYCLOHEXANE-PLATINUM COMPLEXES WITH ANTITUMOR ACTIVITY | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 1988-06-02 | — | — | WO | disclosed |
| EP-0215393-A2 | Platinum(II) complexes of 1,1-cyclobutane-dicarboxylate, a process for preparing them and pharmaceutical compositions containing them | FERRER INTERNACIONAL, S.A. (ES) | 1987-03-25 | — | — | EP | disclosed |